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Glioblastoma, IDH-Mutant

Known as: Secondary Glioblastoma, Secondary Glioblastoma Multiforme, Secondary Glioblastoma, IDH-Mutant 
A glioblastoma arising from a lower grade astrocytoma. It is more commonly seen in younger patients and is associated with IDH1 or IDH2 gene… 
National Institutes of Health

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22 relations
AnaplasiaAstrocytesCentral Nervous SystemGrade four rank

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Identification of Novel Genetic Alterations in Samples of Malignant Glioma Patients
Glioblastoma is the most frequent and malignant human brain tumor. High level of genomic instability detected in glioma cells… 
2012
2012
Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma.
Low-grade glioma is predisposed to progress to anaplastic astrocytoma and eventually secondary glioblastoma. The malignant… 
2009
2009
Phase II trial of sunitinib malate in patients with temozolomide refractory recurrent high-grade glioma.
2005
2005
Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas
To detect and identify the genetic alterations and methylation status of the HRK gene in human glioblastomas, we analyzed a… 
2005
2005
Secondary glioblastoma with advanced neuronal immunophenotype
We describe an unusual progression of astrocytoma into secondary glioblastoma exhibiting advanced neuronal immunophenotype. A… 
2003
2003
Glioblastomatous transformation of ganglioglioma: Case report with reference to molecular genetic and flow cytometric analysis
Gangliogliomas generally behave as benign indolent tumors. However, gangliogliomas undergoing malignant transformation have also… 
1998
1998
Expression of Adhesion Factors and Degrading Proteins in Primary and Secondary Glioblastomas and Their Precursor Tumors
In tumor tissue specimens of 27 primary and 17 secondary glioblastomas and the precursor lesions, the immunohistochemical… 
Highly Cited
1997
Highly Cited
1997
Loss of DCC expression and glioma progression.
The deleted in colorectal cancer (DCC) gene, a candidate tumor suppressor gene on chromosome 18q21, encodes a neural cell… 
1996
1996
Molecular cloning of the cDNA of mouse mitochondrial NADP‐dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation
The current report documents the molecular cloning of the mouse mitochondrial NADP‐dependent isocitrate dehydronegase (mNADP‐IDH… 
1995
1995
Characterization of a cDNA clone for human NAD(+)-specific isocitrate dehydrogenase alpha-subunit and structural comparison with its isoenzymes from different species.
A 0.6 kb cDNA fragment encoding the human NAD(+)-specific isocitrate dehydrogenase alpha-subunit (H-IDH alpha) was amplified by… 
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