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IDH Gene Family
Known as:
IDH
, Isocitrate Dehydrogenase (NADP+) Gene Family
A family of genes that encode enzymes that catalyze the decarboxylation of isocitrate yielding alpha-ketoglutarate and carbon dioxide. Alpha…
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National Institutes of Health
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Related topics
Related topics
7 relations
Glioblastoma, IDH-Mutant
IDH1 wt Allele
IDH2 wt Allele
Isocitrate Dehydrogenase [NADP] Cytoplasmic
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MUTATIONS IN THE IDH GENE (R13211) ARE NOT SUFFICIENT FOR EXPERIMENTAL GLIOMAGENESIS
N. Li
,
K. Sidlauskas
,
+5 authors
S. Brandner
2017
Corpus ID: 79600839
Review
2017
Review
2017
AML in 2017: Advances in clinical practice.
J. Rowe
Baillière's Best Practice & Research: Clinical…
2017
Corpus ID: 42520585
2015
2015
Response to Hypomethylating Agent Therapy in Acute Myeloid Leukemia Based upon Mutations in the DNA Methylation Pathway
Catherine C Coombs
,
S. Devlin
,
+8 authors
Franck Rapaport
2015
Corpus ID: 208463903
Background: Acute myeloid leukemia (AML) is an aggressive malignancy with poor prognosis, especially in the elderly for whom…
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2014
2014
Therapeutics , Targets , and Chemical Biology IDH 1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism
A. Grassian
,
Seth J. Parker
,
+17 authors
Christian M. Metallo
2014
Corpus ID: 37281065
Oncogenic mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) occur in several types of cancer, but the metabolic consequences…
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2014
2014
Targetable signaling pathway mutations and progression of IDH-mutant glioma.
H. Wakimoto
,
Shota Tanaka
,
+16 authors
A. Chi
2014
Corpus ID: 59341781
2061 Background: Isocitrate dehydrogenase (IDH) gene mutations occur in low-grade and high-grade gliomas. We sought to identify…
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Review
2011
Review
2011
Isocitrate dehydrogenase mutations: A challenge to traditional views on the genesis and malignant progression of gliomas
M. Weller
,
W. Wick
,
A. von Deimling
Glia
2011
Corpus ID: 25978029
Isocitrate dehydrogenases (IDHs) convert isocitrate to α‐ketoglutarate by oxidative decarboxylation and are thereby involved in…
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1997
1997
Genetic variability in the European minnow, Phoxinus phoxinus (L.)
G. Müller
,
P. Ward
Hydrobiologia
1997
Corpus ID: 31332271
An electrophoretic study of genetic variation at 11 loci was performedfor a population of European minnows, Phoxinus phoxinus (L…
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1996
1996
Molecular cloning of the cDNA of mouse mitochondrial NADP‐dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation
Liang Yang
,
Hongyu Luo
,
P. Vinay
,
Jiangping Wu
Journal of Cellular Biochemistry
1996
Corpus ID: 20453517
The current report documents the molecular cloning of the mouse mitochondrial NADP‐dependent isocitrate dehydronegase (mNADP‐IDH…
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1996
1996
Expression of human mitochondrial NADP‐dependent isocitrate dehydrogenase during lymphocyte activation
Hongyu Luo
,
Xiaochuan Shan
,
Jiangping Wu
Journal of Cellular Biochemistry
1996
Corpus ID: 35491718
In the process of identifying genes involved in optimization of lymphocyte activation, we have cloned the human mitochondrial…
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