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ICOSLG gene

Known as: GL50, B7 HOMOLOG 2, B7-H2 
This gene is involved in the regulation of T- and B-cell proliferation.
National Institutes of Health

Related topics

Related topics

8 relations
ICOSLG protein, humanImmune System ProcessesInducible T-Cell Co-Stimulator LigandStimulation of Cell Proliferation

Papers overview

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Highly Cited
2016
Highly Cited
2016
The clinical impact of ICOS signal in colorectal cancer patients
ABSTRACT The inducible T-cell co-stimulator (ICOS) belongs to the B7-CD28 immunoglobulin superfamily, which is currently the… 
Highly Cited
2014
Highly Cited
2014
Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome.
Highly Cited
2008
Highly Cited
2008
ICOS/ICOSL Interaction Is Required for CD4+ Invariant NKT Cell Function and Homeostatic Survival1
The development of airway hyperreactivity (AHR), a cardinal feature of asthma, requires the presence of invariant NKT (iNKT… 
Review
2004
Review
2004
Role of T cell costimulation in anti-viral immunity.
Highly Cited
2003
Highly Cited
2003
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
Costimulation through the inducible costimulator (ICOS) and its ligand (ICOSL) is essential for T cell–dependent B cell responses… 
Highly Cited
2003
Highly Cited
2003
Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies.
Inducible co-stimulator ligand (ICOSL), a member of the B7 family of co-stimulatory molecules related to B7.1/2, regulates CD4 as… 
Highly Cited
2000
Highly Cited
2000
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family.
We have isolated the DNMT3L gene that is related to the cytosine-5-methyltransferase 3 (DNMT3) family. The gene is located on… 
Highly Cited
2000
Highly Cited
2000
Cutting Edge: Identification of GL50, a Novel B7-Like Protein That Functionally Binds to ICOS Receptor
By the genetic selection of mouse cDNAs encoding secreted proteins, a B7-like cDNA clone termed mouse GL50 (mGL50) was isolated… 
Highly Cited
2000
Highly Cited
2000
LICOS, a primordial costimulatory ligand?
Highly Cited
2000
Highly Cited
2000
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS.
Optimal T cell activation requires the interactions of co-stimulatory molecules, such as those in the CD28 and B7 protein… 
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