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ICOS wt Allele

Known as: CD278, Activation-Inducible Lymphocyte Immunomediatory Molecule Gene, AILIM 
Human ICOS wild-type allele is located in the vicinity of 2q33 and is approximately 25 kb in length. This allele, which encodes inducible T-cell… 
National Institutes of Health

Related topics

Related topics

7 relations
2q33Acquired HypogammaglobulinemiaICOS protein, humanImmune System Processes

Broader (1)

ICOS gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
JTA-009, a fully human antibody against human AILIM/ICOS, ameliorates graft-vs-host reaction in SCID mice grafted with human PBMCs.
2008
2008
Critical role of activation-inducible lymphocyte immunomediatory molecule/inducible costimulator in the effector function of human T cells: a comparative in vitro study of effects of its blockade and…
2004
2004
AILIM/ICOS signaling induces T-cell migration/polarization of memory/effector T-cells.
AILIM/ICOS has critical roles in the regulation of T-cell differentiation and effector T-cell function in various immune… 
Highly Cited
2003
Highly Cited
2003
PI3-kinase and MAP-kinase signaling cascades in AILIM/ICOS- and CD28-costimulated T-cells have distinct functions between cell proliferation and IL-10 production.
2002
2002
Anticorps anti-AILIM pour le traitment de la maladie de Crohn
On a decouvert qu'un anticorps contre l'AILIM (ou ICOS, ou 8F4) inhibait de maniere significative l'apparition d'affections… 
2001
2001
AILIM/ICOS: its expression and functional analysis with monoclonal antibodies.
Activation-inducible lymphocyte immuno-mediatory molecule (AILIM/ICOS) is the third member of the co-stimulatory molecule CD28… 
2001
2001
Человеческое моноклональное антитело против ailim, костимулирующей молекулы передачи сигнала, и его фармацевтическое применение
Изобретение относится к иммунобиотехнологии и может найти применение в медицине для лечения заболеваний, связанных с AILIM… 
2001
2001
Anticorps monoclonal humain dirige contre une molecule de transduction du signal de co-stimulation ailim et utilisation pharmaceutique de cet anticorps
L'immunisation de souris transgeniques productrices d'anticorps humains, creees a l'aide de techniques du genie genetique, avec… 
2000
2000
Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulatory molecule, related to the CD28/CTLA4 family.
Activation-inducible lymphocyte immuno-mediatory molecule (AILIM) is an inducible cell surface glycoprotein expressed on… 
Review
2000
Review
2000
Special Review AILIM/ICOSの構造と機能--第3のCD28/CTLA4ファミリー分子
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