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ICOS gene

Known as: CD278, AILIM, inducible T-cell co-stimulator 
This gene is involved in the immune response.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response… Expand
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Highly Cited
2011
Highly Cited
2011
The nature of follicular helper CD4(+) T (Tfh) cell differentiation remains controversial, including the minimal signals required… Expand
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Highly Cited
2010
Highly Cited
2010
Human T helper 17 (T(H)17) cells regulate host defense, autoimmunity, and tumor immunity. Although cytokines that control human T… Expand
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Highly Cited
2009
Highly Cited
2009
The inducible costimulatory molecule ICOS has been suggested to be important in the development of interleukin 17 (IL-17… Expand
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Highly Cited
2006
Highly Cited
2006
The homozygous deletion of the inducible costimulator (ICOS), an activation-induced member of the CD28 family on T cells, causes… Expand
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Highly Cited
2004
Highly Cited
2004
CD4+CD25+ T regulatory cells (Tregs) prevent autoimmune disease, yet little is known about precisely where they exert their… Expand
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Highly Cited
2002
Highly Cited
2002
Asthma is caused by T-helper cell 2 (Th2)-driven immune responses, but the immunological mechanisms that protect against asthma… Expand
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Highly Cited
2001
Highly Cited
2001
We examined the requirement for and cooperation between CD28 and inducible costimulator (ICOS) in effective T helper (TH) cell… Expand
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Highly Cited
2000
Highly Cited
2000
Leukocyte traffic through secondary lymphoid tissues is finely tuned by chemokines. We have studied the functional properties of… Expand
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Highly Cited
2000
Highly Cited
2000
Chemokines and their receptors have been identified as major regulators controlling the functional organization of secondary… Expand
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