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ICOS gene

Known as: CD278, AILIM, inducible T-cell co-stimulator 
This gene is involved in the immune response.
National Institutes of Health

Related topics

Related topics

7 relations
Acquired HypogammaglobulinemiaCTLA4 geneICOS protein, humanImmune System Processes

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ICOS wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract SY03-02: Preclinical assessment of JTX-2011, an agonist antibody targeting ICOS, supports evaluation in ICONIC clinical trial
ICOS (the inducible T-cell co-stimulator) is a co-stimulatory molecule expressed on the surface of T cells and a member of the… 
2017
2017
Increased frequency of peripheral blood IL-21 + follicular helper T cells and increased serum IL-21 levels in patients with non-traumatic osteonecrosis of the femoral head
Background: There was no study about follicular helper T (TFH) cells in non-traumatic osteonecrosis of the femoral head (NONFH… 
2016
2016
Abstract 573: Preclinical evaluation of JTX-2011, an anti-ICOS agonist antibody
ICOS (inducible co-stimulator molecule) is a co-stimulatory molecule and a member of the CD28 superfamily expressed primarily on… 
2013
2013
engraftment of allogeneic bone marrow (BM) cells downregulates graft-versus-host disease (GVHD) and facilitates Targeting of inducible costimulator (ICOS) expressed on alloreactive T
2011
2011
Immunologic Reconstitution After Rituximab in Systemic Lupus Erythematosus: Why Should We Care?
There is great interest in the role of B cells in autoimmune inflammatory diseases, running the spectrum from traditionally… 
2009
2009
Genetics of T cell co-stimulatory receptors -CD28, CTLA4, ICOS and PDCD1 in immunity and transplantation
3. Co-stimulatory signals are essential for the activation of naive T cells and productive immune response. Naive T cells receive… 
2008
2008
Expression and Function of the Inducible Costimulator Ligand B 7-H 2 in Human Airway Smooth Muscle Cells
Background: B7-H2 is a ligand for the inducible costimulator (ICOS). The aim of this study was to examine the expression and… 
Review
2005
Review
2005
Expression of Functional B 7-H 2 and B 7 . 2 Costimulatory Molecules andTheir Prognostic Implications in Denovo AcuteMyeloid Leukemia
Purpose:The B7 family molecules have been shown to regulate immune responses in both positive andnegative fashions.Their roles in… 
2003
2003
Partial genomic deletion of ICOS as a cause of hereditary common variable immune deficiency
2002
2002
Role of CD28 and AILIM/ICOS-mediated costimulatory signals in the development of graft versus host disease
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