ICOS gene

Known as: CD278, AILIM, inducible T-cell co-stimulator 
This gene is involved in the immune response.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
0102020002018

Papers overview

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Highly Cited
2011
Highly Cited
2011
The nature of follicular helper CD4(+) T (Tfh) cell differentiation remains controversial, including the minimal signals required… (More)
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Highly Cited
2010
Highly Cited
2010
Human T helper 17 (T(H)17) cells regulate host defense, autoimmunity, and tumor immunity. Although cytokines that control human T… (More)
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Highly Cited
2006
Highly Cited
2006
The homozygous deletion of the inducible costimulator (ICOS), an activation-induced member of the CD28 family on T cells, causes… (More)
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Highly Cited
2004
Highly Cited
2004
CD4+CD25+ T regulatory cells (Tregs) prevent autoimmune disease, yet little is known about precisely where they exert their… (More)
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Highly Cited
2003
Highly Cited
2003
The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did… (More)
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Highly Cited
2002
Highly Cited
2002
Asthma is caused by T-helper cell 2 (Th2)-driven immune responses, but the immunological mechanisms that protect against asthma… (More)
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Highly Cited
2001
Highly Cited
2001
We examined the requirement for and cooperation between CD28 and inducible costimulator (ICOS) in effective T helper (TH) cell… (More)
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Highly Cited
2001
Highly Cited
2001
We describe here a newly identified member of the human B7 family, designated B7 homolog 3 (B7-H3), that shares 20-27% amino acid… (More)
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Highly Cited
2000
Highly Cited
2000
Leukocyte traffic through secondary lymphoid tissues is finely tuned by chemokines. We have studied the functional properties of… (More)
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Highly Cited
2000
Highly Cited
2000
Chemokines and their receptors have been identified as major regulators controlling the functional organization of secondary… (More)
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