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ICOS gene

Known as: CD278, AILIM, inducible T-cell co-stimulator 
This gene is involved in the immune response.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The nature of follicular helper CD4(+) T (Tfh) cell differentiation remains controversial, including the minimal signals required… Expand
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Review
2009
Review
2009
Summary:  T‐cell activation is mediated by antigen‐specific signals from the TCRζ/CD3 and CD4–CD8–p56lck complexes in combination… Expand
Highly Cited
2009
Highly Cited
2009
The inducible costimulatory molecule ICOS has been suggested to be important in the development of interleukin 17 (IL-17… Expand
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Highly Cited
2008
Highly Cited
2008
T cell help to B cells is a fundamental property of adaptive immunity, yet only recently have many of the cellular and molecular… Expand
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Highly Cited
2004
Highly Cited
2004
CD4+CD25+ T regulatory cells (Tregs) prevent autoimmune disease, yet little is known about precisely where they exert their… Expand
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Highly Cited
2002
Highly Cited
2002
Asthma is caused by T-helper cell 2 (Th2)-driven immune responses, but the immunological mechanisms that protect against asthma… Expand
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Highly Cited
2001
Highly Cited
2001
We describe here a newly identified member of the human B7 family, designated B7 homolog 3 (B7-H3), that shares 20–27% amino acid… Expand
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Highly Cited
2001
Highly Cited
2001
We examined the requirement for and cooperation between CD28 and inducible costimulator (ICOS) in effective T helper (TH) cell… Expand
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Highly Cited
2000
Highly Cited
2000
Chemokines and their receptors have been identified as major regulators controlling the functional organization of secondary… Expand
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Highly Cited
2000
Highly Cited
2000
Leukocyte traffic through secondary lymphoid tissues is finely tuned by chemokines. We have studied the functional properties of… Expand
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