ICI 164384

OBJECTIVES Isoflavonoids are discussed for use in chemoprevention and treatment of prostate cancer. We investigated the potential… (More)

The rat estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal ligand binding domain… (More)

The rat estrogen receptor (ER) exists as two subtypes, ERa and ERb, which differ in the C-terminal ligand binding domain and in… (More)

The rat estrogen receptor (ER) exists as two subtypes, ERa and ERb, which differ in the C-terminal ligand binding domain and in… (More)

A novel estrogen receptor (hereinafter referred to as ER beta) was cloned using degenerate PCR primers. A comparison of the amino… (More)

Active cell death in hormone-dependent cells was studied using cultured human mammary carcinoma cells (MCF-7) treated with the… (More)

Genetic and environmental factors can modulate the level of sensitivity to various hormones, including estrogens. Enhanced… (More)

So far, no combination of endocrine treatments has been routinely used in the therapy of breast Cancer. It was, therefore, our… (More)

The transcription of the progesterone receptor gene is induced by estrogens and decreased by progestins. Studies were performed… (More)

The agonistic/antagonistic properties of two non-steroidal antiestrogens, namelytrans-4-monohydroxy-tamoxifen (OH-TAM) and… (More)