Skip to search formSkip to main contentSkip to account menu

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

Known as: Channels, HCN Pacemaker, Pacemaker Channels, HCN, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [Chemical/Ingredient] 
A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (5)

HCN1 ChannelHCN2 potassium channelHCN3 ChannelHCN4 Channel
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation
Hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels mediate pacemaker currents in the atrium. The microRNA… 
Highly Cited
2011
Highly Cited
2011
Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization‐activated cyclic nucleotide‐gated channels in the hippocampus
In hippocampal neurons, synaptic transmission is affected by a variety of modulators, including nitric oxide (NO), which was… 
Highly Cited
2004
Highly Cited
2004
Structural Elements of Instantaneous and Slow Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels*
Hyperpolarization-activated cyclic nucleotide-gated (HCN) subunits produce a slowly activating current in response to… 
Highly Cited
2003
Highly Cited
2003
Genes Encoding Proteins of the Cation Diffusion Facilitator Family That Confer Manganese Tolerance Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10…
The yeast Saccharomyces cerevisiae expressing a cDNA library prepared from Stylosanthes hamata was screened for enhanced Mn2… 
Highly Cited
2002
Highly Cited
2002
Clade-specific morphological diversification and adaptive radiation in Hawaiian songbirds
The Hawaiian honeycreepers are a dramatic example of adaptive radiation but contrast with the four other songbird lineages that… 
Highly Cited
2001
Highly Cited
2001
C Terminus-mediated Control of Voltage and cAMP Gating of Hyperpolarization-activated Cyclic Nucleotide-gated Channels*
The hyperpolarization-activated cyclic nucleotide-gated (HCN) family of “pacemaker” channels includes 4 isoforms, the kinetics… 
Highly Cited
1998
Highly Cited
1998
Mitochondrial ATP-sensitive K+ channels modulate cardiac mitochondrial function.
Discovered in the cardiac sarcolemma, ATP-sensitive K+(KATP) channels have more recently also been identified within the inner… 
Highly Cited
1993
Highly Cited
1993
Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel
Highly Cited
1992
Highly Cited
1992
Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells.
Highly Cited
1972
Highly Cited
1972
A23187: a divalent cation ionophore.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)