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Hyperinsulinism
Known as:
hyperinsulinaemia
, Hyperinsulinism [Disease/Finding]
, increasing insulin
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A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion…
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National Institutes of Health
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Related topics
Related topics
29 relations
Alstrom Syndrome
Congenital Generalized Lipodystrophy Type 1
Congenital Generalized Lipodystrophy Type 2
Donohue Syndrome
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Narrower (3)
Compensatory Hyperinsulinemia
Endogenous Hyperinsulinism
Metabolic Syndrome X
Broader (3)
Endocrine Pancreas Disorder
Endocrine System Diseases
disorder of carbohydrate metabolism
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Increased β-Oxidation in Muscle Cells Enhances Insulin-stimulated Glucose Metabolism and Protects against Fatty Acid-induced Insulin Resistance Despite Intramyocellular Lipid Accumulation*
Germán Perdomo
,
S. Commerford
,
+4 authors
N. Brown
Journal of Biological Chemistry
2004
Corpus ID: 11382115
Skeletal muscle insulin resistance may be aggravated by intramyocellular accumulation of fatty acid-derived metabolites that…
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Highly Cited
1999
Highly Cited
1999
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats.
A. B. Walker
,
P. Chattington
,
R. Buckingham
,
G. Williams
Diabetes
1999
Corpus ID: 7743547
Human obesity is associated with insulin resistance, hyperinsulinemia, and a predisposition to hypertension and vascular disease…
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Highly Cited
1999
Highly Cited
1999
Lipodystrophy defined by a clinical score in HIV-infected men on highly active antiretroviral therapy: correlation between dyslipidaemia and steroid hormone alterations.
Névéna Christeff
,
Jean-Claude Melchior
,
Pierre de Truchis
,
Christian Perronne
,
Emmanuel A. Nunez
,
Marie-Lise Gougeon
AIDS (London)
1999
Corpus ID: 6214551
BACKGROUND A syndrome of lipodystrophy, associated with hypertriglyceridaemia, hypercholesterolaemia, hyperinsulinaemia and…
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Highly Cited
1998
Highly Cited
1998
Perturbation of Fuel Homeostasis Caused by Overexpression of the Glucose-6-phosphatase Catalytic Subunit in Liver of Normal Rats*
K. Trinh
,
R. O’Doherty
,
P. Anderson
,
A. Lange
,
C. Newgard
Journal of Biological Chemistry
1998
Corpus ID: 8221088
The terminal step in hepatic gluconeogenesis is catalyzed by glucose-6-phosphatase, an enzyme activity residing in the…
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Highly Cited
1998
Highly Cited
1998
The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.
Y. Sato
,
J. Henquin
Diabetes
1998
Corpus ID: 28483419
By closing ATP-sensitive K+ (K+-ATP) channels, glucose promotes depolarization-dependent Ca2+ entry and cytoplasmic free Ca2…
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Highly Cited
1991
Highly Cited
1991
Effects of growth hormone on fuel utilization and muscle glycogen synthase activity in normal humans.
J. Bak
,
N. Møller
,
O. Schmitz
American Journal of Physiology
1991
Corpus ID: 35397531
To examine the insulin antagonistic effects of growth hormone (GH), seven healthy subjects underwent, in random order, two 5-h…
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Highly Cited
1981
Highly Cited
1981
Glucose Disposal is Not Proportional to Plasma Glucose Level in Man
J. Best
,
G. Taborsky
,
J. Halter
,
D. Porte
Diabetes
1981
Corpus ID: 45615522
Metabolic clearance rate (MCR) of glucose has been defined as the rate of glucose utilization divided by the glucose…
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Highly Cited
1979
Highly Cited
1979
Increased insulin binding to erythrocytes in anorexia nervosa: restoration to normal with refeeding.
H. Wachslicht-Rodbard
,
H. Gross
,
D. Rodbard
,
M. Ebert
,
J. Roth
New England Journal of Medicine
1979
Corpus ID: 31727995
We studied [125I] insulin binding to circulating cells in patients with anorexia nervosa (eight females), in the basal cachectic…
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Highly Cited
1979
Highly Cited
1979
The insulin resistance of acromegaly: evidence for two alterations in the insulin receptor on circulating monocytes.
M. Muggeo
,
R. S. Bar
,
J. Roth
,
C. Kahn
,
P. Gorden
Journal of Clinical Endocrinology and Metabolism
1979
Corpus ID: 44759796
[125I]Insulin binding to insulin receptors on circulating monocytes was studied in 11 patients with acromegaly (human GH, 7–240…
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Highly Cited
1959
Highly Cited
1959
Increased Circulating Insulin-like Activity in Obese-Hyperglycæmic Mice
J. Christophe
,
Y. Dagenais
,
J. Mayer
Nature
1959
Corpus ID: 31772467
THE hereditary obese-hyperglycæmic syndrome of mice is a condition characterized by extreme adiposity, hyperglycæmia…
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