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Hyperinsulinism

Known as: hyperinsulinaemia, Hyperinsulinism [Disease/Finding], increasing insulin 
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion… 
National Institutes of Health

Related topics

Related topics

29 relations
Alstrom SyndromeCongenital Generalized Lipodystrophy Type 1Congenital Generalized Lipodystrophy Type 2Donohue Syndrome

Narrower (3)

Compensatory HyperinsulinemiaEndogenous HyperinsulinismMetabolic Syndrome X

Broader (3)

Endocrine Pancreas DisorderEndocrine System Diseasesdisorder of carbohydrate metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
AMPK, insulin resistance, and the metabolic syndrome.
Insulin resistance (IR) and hyperinsulinemia are hallmarks of the metabolic syndrome, as are central adiposity, dyslipidemia, and… 
Review
2010
Review
2010
Pathogenesis of Insulin Resistance in Skeletal Muscle
Insulin resistance in skeletal muscle is manifested by decreased insulin-stimulated glucose uptake and results from impaired… 
Highly Cited
2005
Highly Cited
2005
Neonatal leptin treatment reverses developmental programming.
An adverse prenatal environment may induce long-term metabolic consequences, in particular obesity and insulin resistance… 
Highly Cited
2005
Highly Cited
2005
The metabolically healthy but obese individual presents a favorable inflammation profile.
OBJECTIVE The purpose of this study was to investigate the inflammatory state in obese women displaying the "metabolically… 
Highly Cited
2003
Highly Cited
2003
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.
The serine/threonine kinase Akt/PKB plays key roles in the regulation of cell growth, survival, and metabolism. It remains… 
Highly Cited
2002
Highly Cited
2002
The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes.
We examined the effect of three months of rosiglitazone treatment (4 mg b.i.d.) on whole-body insulin sensitivity and in vivo… 
Review
2001
Review
2001
The somatomedin hypothesis: 2001.
Since the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify… 
Highly Cited
1988
Highly Cited
1988
Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in Pima Indians.
Impaired glucose tolerance often presages the development of non-insulin-dependent diabetes mellitus. We have studied insulin… 
Highly Cited
1985
Highly Cited
1985
The Effect of Insulin Treatment on Insulin Secretion and Insulin Action in Type II Diabetes Mellitus
We have studied the effects of 3 wk of continuous subcutaneous insulin infusion (CSII) on endogenous insulin secretion and action… 
Highly Cited
1969
Highly Cited
1969
Pancreatic glucagon secretion in normal and diabetic subjects.
Availability of a relatively specific antiserum to glucagon has made possible studies of alpha cell function in man. In healthy… 
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