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Hyperalgesia

Known as: hyperalgia, Hyperalgesic Sensations, hyperpathia 
An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids. The condition… Expand
Review
2009
Review
2009
Hyperalgesia and allodynia are frequent symptoms of disease and may be useful adaptations to protect vulnerable tissues. Both may… Expand
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Review
2006
Review
2006
Opioids are the cornerstone therapy for the treatment of moderate to severe pain. Although common concerns regarding the use of… Expand
Highly Cited
2002
Highly Cited
2002
Peripheral inflammation induces p38 MAPK activation in the soma of C fiber nociceptors in the dorsal root ganglion (DRG) after 24… Expand
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Highly Cited
2000
Highly Cited
2000
The vanilloid receptor-1 (VR1) is a ligand-gated, non-selective cation channel expressed predominantly by sensory neurons. VR1… Expand
Review
1994
Review
1994
Although physiological stimuli in the healthy gastrointestinal tract are generally not associated with conscious perception… Expand
Review
1992
Review
1992
Hyperalgesia after cutaneous injury can be divided into two phenomena: Primary hyperalgesia occurs at the site of injury and is… Expand
Highly Cited
1992
Highly Cited
1992
Inhibition of cyclooxygenase by nonsteroidal anti-inflammatory drugs (NSAIDs) in the periphery is commonly accepted as the… Expand
Highly Cited
1991
Highly Cited
1991
1. Psychophysical studies were made, in humans, of the sensory characteristics and underlying mechanisms of the hyperalgesia… Expand
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Highly Cited
1988
Highly Cited
1988
&NA; A method to measure cutaneous hyperalgesia to thermal stimulation in unrestrained animals is described. The testing paradigm… Expand