Conditioning and hyperalgesia in newborns exposed to repeated heel lances.

@article{Taddio2002ConditioningAH,
  title={Conditioning and hyperalgesia in newborns exposed to repeated heel lances.},
  author={Anna Taddio and Vibhuti S. Shah and Cheryl Gilbert-MacLeod and Joel Katz},
  journal={JAMA},
  year={2002},
  volume={288 7},
  pages={
          857-61
        }
}
CONTEXT Hospitalized infants undergo repeated invasive procedures. It is unknown whether cumulative experiences with pain lead to anticipatory pain behaviors and hyperalgesia. OBJECTIVES To determine whether newborns who are born to mothers with diabetes and undergo repeated pain learn to anticipate pain and exhibit more pain during a painful procedure than normal infants. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study of 21 full-term newborns born to mothers with diabetes and… CONTINUE READING
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