Hydroxymethyltransferases

Known as: Formyltransferases, formininotransferase, Transhydroxymethylases 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
0204019562016

Papers overview

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Highly Cited
2005
Highly Cited
2005
Gemcitabine and pemetrexed are effective agents in the treatment of non-small-cell lung cancer (NSCLC), and the present study… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Methotrexate (MTX) enters cells through the reduced folate carrier (RFC-1) and exerts part of its effects through… (More)
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Highly Cited
2002
Highly Cited
2002
We previously reported that 2 polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene at positions C677T and… (More)
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Highly Cited
2000
Highly Cited
2000
Anaplastic lymphoma kinase (ALK)-positive lymphomas ("ALKomas") constitute a distinct molecular and clinicopathological entity… (More)
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Highly Cited
1997
Highly Cited
1997
N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl ]-benzoyl]-L-glutamic acid (LY231514) is a novel pyrrolo… (More)
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Highly Cited
1995
Highly Cited
1995
The transport properties and growth-inhibitory potential of 37 classic and novel antifolate compounds have been tested in vitro… (More)
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Highly Cited
1991
Highly Cited
1991
Although commonly used to control a variety of inflammatory diseases, the mechanism of action of a low dose of methotrexate… (More)
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Highly Cited
1989
Highly Cited
1989
5,10-Dideazatetrahydrofolate (DDATHF) is a new antimetabolite designed as an inhibitor of folate metabolism at sites other than… (More)
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Highly Cited
1985
Highly Cited
1985
We report the enhanced inhibitory potency of methotrexate (MTX) polyglutamates and dihydrofolate pentaglutamate on the catalytic… (More)
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1981
1981
Three allelic mutants of Arabidopsis thaliana which lack mitochondrial serine transhydroxymethylase activity due to a recessive… (More)
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