Glycine Hydroxymethyltransferase

Known as: Threonine Aldolase, Serine Hydroxymethylase, Hydroxymethyltransferase, Glycine 
A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Cancer cells adapt their metabolic processes to support rapid proliferation, but less is known about how cancer cells alter… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2013
Review
2013
Glycine is a major amino acid in mammals and other animals. It is synthesized from serine, threonine, choline, and hydroxyproline… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Review
2007
Review
2007
The vitamin B(6)-derived pyridoxal 5'-phosphate (PLP) is the cofactor of enzymes catalyzing a large variety of chemical reactions… (More)
Is this relevant?
Review
2005
Review
2005
Recent structural data and the properties of several active site mutants of serine hydroxymethyltransferase have resolved some… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Folate-dependent one-carbon metabolism is required for the synthesis of purines and thymidylate and for the remethylation of… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
We previously reported that 2 polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene at positions C677T and… (More)
  • figure 1
  • table 1
  • table 3
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
A cDNA library enriched with Myc-responsive cDNAs but depleted of myc cDNAs was used in a functional screen for growth… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2001
Review
2001
The mitochondrial glycine decarboxylase multienzyme system, connected to serine hydroxymethyltransferase through a soluble pool… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Neural tube defects (NTD) arise in the first weeks of pregnancy due to a combination of environmental and genetic factors. In… (More)
Is this relevant?
Highly Cited
1985
Highly Cited
1985
Serine hydroxymethyltransferase from Escherichia coli was purified to homogeneity. The enzyme was a homodimer of identical… (More)
  • table 1
  • figure 1
  • table 2
  • figure 3
  • figure 2
Is this relevant?