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Hydroxyacetylaminofluorene

Known as: Acetamide, N-9H-fluoren-2-yl-N-hydroxy-, Hydroxyacetylaminofluorene [Chemical/Ingredient], Hydroxyfluorenylacetamide 
A N-hydroxylated derivative of 2-ACETYLAMINOFLUORENE that has demonstrated carcinogenic action.
National Institutes of Health

Papers overview

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1986
1986
The mechanism-based inactivation (suicide inactivation) by N-hydroxyphenacetin (NHP) of N-arylhydroxamic acid N,O-acyltransferase… Expand
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Highly Cited
1985
Highly Cited
1985
A new enzymatic activation of mutagenic N-hydroxyarylamines is described. An acetyl-CoA dependent enzyme that can activate 2… Expand
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1985
1985
N-Arylhydroxamic acid N,O-acyltransferase (AHAT) catalyzes the transfer of the N-acetyl group from N-arylhydroxamic acids to… Expand
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1982
1982
The synthesis of a series of 12 N-(2-fluorenyl)hydroxamic acids, N-(2-fluorenyl)-N-hydroxyureas, and N-(2-fluorenyl)-N… Expand
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1980
1980
1. Ag.l.c. assay for N-hydroxy-2-acetamidofluorene has been modified to measure both N-hydroxy-2-acetamidofluorene and N-hydroxy… Expand
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1975
1975
The sulfate and acetate esters of the carcinogen N-hydroxy-2-acetamidophenanthrene attack calf thymus DNA in vitro to yield… Expand
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1975
1975
  • F. Becker
  • Cancer research
  • 1975
  • Corpus ID: 14436977
These experiments examined the effects of a single, subcarcinogenic dose of dimethylnitrosamine or N-hydroxyfluorenylacetamide… Expand
  • table 1
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1968
1968
ImagesFigs. 6-7Figs. 8-9Figs. 10-11Figs. 2-3Figs. 4-5 
  • figure 1
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1965
1965
FOLLOWING the original observation of Cramer, Miller and Miller (1960) that an N-hydroxylated metabolite of 2-acetamidofluorene… Expand
  • figure 1
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