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Homozygote

Known as: Homozygous, homozygous genotype, Homozygosity 
Occurs when both alleles at a particular gene locus are the same. A person may be homozygous for the normal allele or for a mutation.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Genotype
pure line

Papers overview

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Highly Cited
2001
Highly Cited
2001
Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia.
We have previously shown that familial septo-optic dysplasia (SOD), a syndromic form of congenital hypopituitarism involving… 
Highly Cited
2000
Highly Cited
2000
A Single-Transformation Gene Function Test in DiploidCandida albicans
ABSTRACT The fungal pathogen Candida albicans is naturally diploid, and current gene disruption strategies require two successive… 
Highly Cited
1998
Highly Cited
1998
Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants.
It is now well known that the initial phase of graft-versus-host disease (GVHD) involves cytokine release during preconditioning… 
Highly Cited
1997
Highly Cited
1997
Heterozygosity for a deletion in the CKR‐5 gene leads to prolonged AIDS‐free survival and slower CD4 T‐cell decline in a cohort of HIV‐seropositive individuals
Objective:Recently, it has been shown that a homozygous 32 base-pair deletion in the gene encoding CKR-5, a major coreceptor for… 
Highly Cited
1994
Highly Cited
1994
Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck.
Sixty-eight primary head and neck squamous cell carcinomas and nine head and neck squamous cell carcinoma cell lines were… 
Highly Cited
1994
Highly Cited
1994
Unraveling selection in the mitochondrial genome of Drosophila.
We examine mitochondrial DNA variation at the cytochrome b locus within and between three species of Drosophila to determine… 
Highly Cited
1983
Highly Cited
1983
DNA POLYMORPHISM ADJACENT TO HUMAN APOPROTEIN A-1 GENE: RELATION TO HYPERTRIGLYCERIDAEMIA
Highly Cited
1976
Highly Cited
1976
Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein
Highly Cited
1976
Highly Cited
1976
Inherited deficiency of the second component of complement. Rheumatic disease associations.
The prevalence of homozygous and heterozygous deficiency of the second component of complement (C2) was determined in patients… 
Highly Cited
1962
Highly Cited
1962
THE HISTOLOGICAL DISTRIBUTION OF THE BLOOD GROUP SUBSTANCES IN MAN AS DISCLOSED BY IMMUNOFLUORESCENCE
The H antigen was mapped out by immunofluorescence in human tissues (including those of fetuses from 15 cm crown-heel length… 
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