Homozygote

Known as: Homozygous, homozygous genotype, Homozygosity 
Occurs when both alleles at a particular gene locus are the same. A person may be homozygous for the normal allele or for a mutation.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Importance Autosomal recessive inherited neurodevelopmental disorders are highly heterogeneous, and many, possibly most, of the… (More)
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Highly Cited
2009
Highly Cited
2009
Genome-wide association studies suggest that common genetic variants explain only a modest fraction of heritable risk for common… (More)
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Highly Cited
2006
Highly Cited
2006
Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other tissues. We now show that the… (More)
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Highly Cited
2005
Highly Cited
2005
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM) are clonal disorders… (More)
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Highly Cited
2005
Highly Cited
2005
The CLOCK transcription factor is a key component of the molecular circadian clock within pacemaker neurons of the hypothalamic… (More)
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Highly Cited
2004
Highly Cited
2004
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of tissues during ageing in humans, monkeys… (More)
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Review
1997
Review
1997
These results clearly point out that p53 uses a hyThe p53 gene and its protein product have become the drophobic interface in its… (More)
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Highly Cited
1997
Highly Cited
1997
The induction of phase II detoxifying enzymes is an important defense mechanism against intake of xenobiotics. While this group… (More)
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Highly Cited
1992
Highly Cited
1992
Gene targeting in embryonic stem (ES) cells has been used to mutate the murine DNA methyltransferase gene. ES cell lines… (More)
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Highly Cited
1991
Highly Cited
1991
OF the various classes of antibodies that B lymphocytes can produce, class M (IgM) is the first to be expressed on the membrane… (More)
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