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Homozygote

Known as: Homozygous, homozygous genotype, Homozygosity 
Occurs when both alleles at a particular gene locus are the same. A person may be homozygous for the normal allele or for a mutation.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Genotype
pure line

Papers overview

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Highly Cited
2005
Highly Cited
2005
Mutation studies in CD3+, CD19+ and CD34+ cell fractions in myeloproliferative disorders with homozygous JAK2V617F in granulocytes
amplified by polymerase chain reaction (http://research.nhgri.nih.Gov/bic/), and each amplicon was sequenced in both forward and… 
Highly Cited
2000
Highly Cited
2000
Growing-finishing performance and carcass characteristics of pigs fed normal and genetically modified low-phytate corn.
A genetically modified corn hybrid homozygous for the lpa1 allele, containing low phytate (LP), and its nearly isogenic… 
Highly Cited
1986
Highly Cited
1986
Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.
We have isolated and sequenced cDNA clones corresponding to the DR beta 1 and DR beta 2 loci from two homozygous B-cell lines… 
Highly Cited
1985
Highly Cited
1985
Human growth hormone gene deletion without antibody formation or growth arrest during treatment--a new disease entity?
Using restriction endonuclease analysis of genomic DNA hybridized to a human chorionic somatomammotropin (hCS) complementary (c… 
1980
1980
Chromosomal localization of ev-1, a frequently occurring endogenous retrovirus locus in white Leghorn chickens, by in situ hybridization
The distribution of 12 endogenous retrovirus loci from 13 White Leghorn flocks of diverse geographical origin was examined, using… 
Highly Cited
1977
Highly Cited
1977
Comparison of the biliary excretion of the four isomers of bilirubin-IX in Wistar and homozygous Gunn rats.
The biliary excretion of the four isomers of bilirubin-IX was studied in Wistar rats (JJ) and homozygous Gunn rats (jj… 
Review
1976
Review
1976
The unit of selection in Drosophila mercatorum. I. The interation of selection and meiosis in parthenogenetic strains.
An important problem in population genetics is the determination of the level of genetic organization to which fitness measures… 
Highly Cited
1973
Highly Cited
1973
Typing for MLC determinants by means of LD-homozygous and LD-heterozygous test cells.
Highly Cited
1973
Highly Cited
1973
Evidence for control of several different tissue-specific isozymes of adenosine deaminase by a single genetic locus.
ADENOSINE deaminase is found in several different forms in human tissues. In red blood cells, adenosine deaminase activity is… 
Highly Cited
1971
Highly Cited
1971
Photocatabolism of labeled bilirubin in the congenitally jaundiced (Gunn) rat.
To elucidate the mechanism by which phototherapy reduces serum bilirubin, studies were performed on the catabolism of labeled…