Homogeneously Staining Region

Known as: hsr 
A region on a chromosome which, when stained, is uniform in appearance. (Normally, a stained chromosome shows a banding pattern.) Homogeneously… (More)
National Institutes of Health

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Papers overview

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Review
2009
Review
2009
Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research.
Gene amplification in human cancer cells generates two cytogenetically identifiable structures: extrachromosomal double minutes… (More)
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2005
2005
Del(5q) and MLL amplification in homogeneously staining region in acute myeloblastic leukemia: a recurrent cytogenetic association
We report here a 71 year-old female presenting with acute myeloblastic leukemia (FAB-M1) after treatment of essential… (More)
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2004
2004
Macroscopic folding and replication of the homogeneously staining region in late S phase leads to the appearance of replication bands in mitotic chromosomes.
The chromosomal G/R bands are alternating domains differing in their nucleotide sequence biases. The bands are also related to… (More)
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Highly Cited
1998
Highly Cited
1998
Interphase Cell Cycle Dynamics of a Late-Replicating, Heterochromatic Homogeneously Staining Region: Precise Choreography of Condensation/Decondensation and Nuclear Positioning
Recently we described a new method for in situ localization of specific DNA sequences, based on lac operator/repressor… (More)
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1993
1993
In situ hybridisation analysis of a homogeneously staining region at 11q23-24 in an acute myeloid leukaemia (M5) using yeast artificial chromosomes.
An example of a homogeneously staining region (hsr), occurring in an acute myeloid leukaemia (M5) on chromosome 11 in the region… (More)
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1992
1992
Homogeneously staining region in anthracycline-resistant HL-60/AR cells not associated with MDR1 amplification.
Anthracycline-resistant HL-60/AR cells and their drug-sensitive HL-60/S counterparts were characterized by karyotypic analysis… (More)
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1983
1983
Homogeneously staining regions and tumorigenicity.
A homogeneously staining region (HSR), a chromosome abnormality associated with gene amplification, was found to increase in… (More)
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1983
1983
Correlation of unstable multidrug cross resistance in Chinese hamster ovary cells with a homogeneously staining region on chromosome 1.
An enrichment selection method using repeated pulses of low drug concentration (1 microgram/ml) was used to isolate CHO (AK412… (More)
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1981
1981
Homogeneously staining region in a retinoblastoma cell line: relevance to tumor initiation and progression.
A human retinoblastoma cell line was found to contain a homogeneously staining region (HSR) on chromosome 1 (at 1p34). An HSR had… (More)
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1979
1979
Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells
A methotrexate (MTX)-resistant murine lymphoblastoid cell line has been obtained by serial passage in increasing concentrations… (More)
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