Histone H3 Dimethyl Lys4

Known as: H3K4me2, H3K4me2 Antigen 
A post-translationally modified form of histone H3 where the lysine residue at position 4 is dimethylated. This modification may be a marker for… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
020406020032017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
Acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML), characterized by the t(15… (More)
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Highly Cited
2011
Highly Cited
2011
Integrative epigenomic mapping defines four main chromatin states in Arabidopsis
Post-translational modification of histones and DNA methylation are important components of chromatin-level control of genome… (More)
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Highly Cited
2010
Highly Cited
2010
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
In higher eukaryotes, histone methylation is involved in maintaining cellular identity during somatic development. As most… (More)
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Highly Cited
2009
Highly Cited
2009
Distinctive Chromatin in Human Sperm Packages Genes for Embryo Development
Because nucleosomes are widely replaced by protamine in mature human sperm, the epigenetic contributions of sperm chromatin to… (More)
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Highly Cited
2009
Highly Cited
2009
Global levels of histone modifications predict prognosis in different cancers.
Cancer cells exhibit alterations in histone modification patterns at individual genes and globally at the level of single nuclei… (More)
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Highly Cited
2009
Highly Cited
2009
Dimethylation of H3K4 by Set1 Recruits the Set3 Histone Deacetylase Complex to 5′ Transcribed Regions
Cotranscriptional histone methylations by Set1 and Set2 have been shown to affect histone acetylation at promoters and 3' regions… (More)
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Highly Cited
2008
Highly Cited
2008
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Regulatory T (Treg) cells safeguard against autoimmunity and immune pathology. Because determinants of the Treg cell fate are not… (More)
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Highly Cited
2008
Highly Cited
2008
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana
Post-translational modifications of histones play important roles in maintaining normal transcription patterns by directly or… (More)
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Highly Cited
2007
Highly Cited
2007
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive
Eukaryotic genomes are organized into active (euchromatic) and inactive (heterochromatic) chromatin domains. Post-translational… (More)
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Highly Cited
2006
Highly Cited
2006
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
Dynamic regulation of diverse nuclear processes is intimately linked to covalent modifications of chromatin. Much attention has… (More)
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