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Histone H3 Dimethyl Lys4

Known as: H3K4me2, H3K4me2 Antigen 
A post-translationally modified form of histone H3 where the lysine residue at position 4 is dimethylated. This modification may be a marker for… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Dynamic changes in histone modifications precede de novo DNA methylation in oocytes
In mouse oogenesis, DNA methylation establishment occurs on a largely unmethylated genome and in nondividing cells, making it a… 
Highly Cited
2014
Highly Cited
2014
Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC
Highly Cited
2013
Highly Cited
2013
Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
Here, we describe that lysine-specific demethylase 1 (Lsd1/KDM1a), which demethylates histone H3 on Lys4 or Lys9 (H3K4/K9), is an… 
Highly Cited
2012
Highly Cited
2012
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
Acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML), characterized by the t(15… 
Highly Cited
2010
Highly Cited
2010
Epigenetic histone methylation modulates fibrotic gene expression.
TGF-β1-induced expression of extracellular matrix (ECM) genes plays a major role in the development of chronic renal diseases… 
Highly Cited
2010
Highly Cited
2010
Dynamic changes in genome-wide histone H3 lysine 4 methylation patterns in response to dehydration stress in Arabidopsis thaliana
BackgroundThe molecular mechanisms of genome reprogramming during transcriptional responses to stress are associated with… 
Highly Cited
2010
Highly Cited
2010
Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704.
PURPOSE Differences in cellular levels of histone modifications have predicted clinical outcome in certain cancers. Here, we… 
Highly Cited
2010
Highly Cited
2010
High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors.
Integration of retroviral vectors in the human genome follows nonrandom patterns that favor insertional deregulation of gene… 
Highly Cited
2009
Highly Cited
2009
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana
BackgroundPost-translational modifications of histones play important roles in maintaining normal transcription patterns by… 
Highly Cited
2007
Highly Cited
2007
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
Epigenetic chromatin modification is a major regulator of eukaryotic gene expression, and aberrant epigenetic silencing of gene… 
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