High-Throughput Screening Assays

Known as: High-Throughput Screening Assay, Screening Assay, High-Throughput, High Throughput Screening Assays 
Rapid methods of measuring the effects of an agent in a biological or chemical assay. The assay usually involves some form of automation or a way to… (More)
National Institutes of Health

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Combinatorial Chemistry TechniquesDrug DiscoverySmall Molecule Librariesstandards characteristics

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High-Throughput Biological AssaysHigh-Throughput Chemical AssaysHigh-Throughput Screening Methods

Papers overview

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2014
2014
High-Throughput Screening Platform for Engineered Nanoparticle-Mediated Genotoxicity Using CometChip Technology
The likelihood of intentional and unintentional engineered nanoparticle (ENP) exposure has dramatically increased due to the use… (More)
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2012
2012
Validating a firefly luciferase-based high-throughput screening assay for antimalarial drug discovery.
The emergence and spread of multidrug-resistant Plasmodium falciparum and recent detection of potential artemisinin-resistant… (More)
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Highly Cited
2011
Highly Cited
2011
3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen.
Despite advancements in therapies developed for the treatment of cancer, patient prognosis and mortality rates have improved… (More)
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Highly Cited
2007
Highly Cited
2007
A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays.
RNA interference (RNAi) high-throughput screening (HTS) enables massive parallel gene silencing and is increasingly being used to… (More)
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2007
2007
Alternative statistical parameter for high-throughput screening assay quality assessment.
High-throughput screening is an essential process in drug discovery. The ability to identify true active compounds depends on the… (More)
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2007
2007
Correctors of protein trafficking defects identified by a novel high-throughput screening assay.
High-throughput small-molecule screens hold great promise for identifying compounds with potential therapeutic value in the… (More)
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Highly Cited
2004
Highly Cited
2004
Sniffing out the correct physical layer capture model in 802.11b
Physical layer capture (PLC) in 802.11b refers to the successful reception of the stronger (higher signal strength at receiver… (More)
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Highly Cited
2003
Highly Cited
2003
IEEE 802.11b Ad Hoc Networks: Performance Measurements
In this paper we investigate the performance of IEEE 802.11b ad hoc networks by means of an experimental study. An extensive… (More)
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2002
2002
Optimization and phase transitions in a chaotic model of data traffic.
Ohira and Sawatari [Phys. Rev E 58, 193 (1998)] introduced a simple model for a packet-switching network which was extended by… (More)
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2000
2000
Challenges and solutions to ultra-high-throughput screening assay miniaturization: submicroliter fluid handling.
The miniaturization of HTS assays is an important objective in the pharmaceutical industry. The ability to perform primary… (More)
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