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Drug Discovery

Known as: Discovery, Drug, discoveries drug, discovery drug 
The process of finding chemicals for potential therapeutic use.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
ChEMBL is an Open Data database containing binding, functional and ADMET information for a large number of drug-like bioactive… 
Highly Cited
2011
Highly Cited
2011
We describe a graphical system for automatically generating multiple 2D diagrams of ligand-protein interactions from 3D… 
Review
2008
Review
2008
  • A. Hopkins
  • Nature chemical biology
  • 2008
  • Corpus ID: 1450172
The dominant paradigm in drug discovery is the concept of designing maximally selective ligands to act on individual drug targets… 
Highly Cited
2006
Highly Cited
2006
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive… 
Review
2005
Review
2005
Natural products and their derivatives have historically been invaluable as a source of therapeutic agents. However, in the past… 
Review
2005
Review
2005
Evolving studies with several different targeted therapeutic agents are demonstrating that patients with genomic alterations of… 
Review
2004
Review
2004
Computational approaches that 'dock' small molecules into the structures of macromolecular targets and 'score' their potential… 
Highly Cited
2000
Highly Cited
2000
Driven by chemistry but increasingly guided by pharmacology and the clinical sciences, drug research has contributed more to the… 
Highly Cited
1990
Highly Cited
1990
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and…