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Drug Discovery
Known as:
Discovery, Drug
, discoveries drug
, discovery drug
The process of finding chemicals for potential therapeutic use.
National Institutes of Health
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Related topics
Related topics
5 relations
Bioprospecting
Educational aspects
High-Throughput Screening Assays
legislation & jurisprudence
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
S. Small
,
G. Petsko
Nature Reviews Neuroscience
2015
Corpus ID: 43512447
Nature Reviews Neuroscience 16, 126–132 (2015) In the abstract for this article, the second line was incorrect. It should have…
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Review
2012
Review
2012
PULSATILE: A TOOL FOR CIRCARDIAN RHYTHM - A REVIEW
M. Modi
,
V. PrasanthV.
,
S. Mathew
2012
Corpus ID: 54115718
In the field of modified release, this review covers the detail aspect of a novel pulsatile drug delivery systems (PDDS) by oral…
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2008
2008
Antibacterial activity of solvent fractions of crude water decoction of apical twigs and latex of Calotropis procera (Ait.) R. Br.
Farzin M. Parabia
,
I. L. Kothari
,
M. Parabia
2008
Corpus ID: 86011106
Water decoction of Calotropis procera (Ait.) R.Br. is reported as a purulent wound healer in Indian System of Medicine — Ayurveda…
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2005
2005
Pharmacogenomics and the Drug Discovery Pipeline
M. Penny
,
D. McHale
2005
Corpus ID: 86477735
One of the key factors in developing improved medicines lies in understanding the molecular basis of the complex diseases we…
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Highly Cited
2003
Highly Cited
2003
High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma.
Y. Hsieh
,
K. Merkle
,
Ganfeng Wang
,
J. Brisson
,
Walter A. Korfmacher
Analytical Chemistry
2003
Corpus ID: 27734435
A generic high-performance liquid chromatography (HPLC) system interfaced with an atmospheric pressure photoionization (APPI…
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2003
2003
Tyrosine kinase targets in drug discovery
K. Grosios
,
P. Traxler
2003
Corpus ID: 71265230
Protein tyrosine kinases are central to the signal transduction machinery of healthy cells and their deregulation plays a causal…
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Highly Cited
2001
Highly Cited
2001
Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry.
Y. Hsieh
,
M. Chintala
,
+4 authors
Walter A. Korfmacher
Rapid Communications in Mass Spectrometry
2001
Corpus ID: 42167467
A higher-throughput bioanalytical method based on fast-gradient (1 min run time) high-performance liquid chromatography (HPLC…
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2000
2000
Direct analysis of plasma samples for drug discovery compounds using mixed-function column liquid chromatography tandem mass spectrometry.
Y. Hsieh
,
M. Bryant
,
G. Gruela
,
J. Brisson
,
Walter A. Korfmacher
Rapid Communications in Mass Spectrometry
2000
Corpus ID: 45017627
A sensitive, efficient, high throughput, direct injection bioanalytical method based on a single column and high-performance…
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2000
2000
Quantitative Molecular Pharmacology and Informatics in Drug Discovery
M. Lutz
,
T. Kenakin
2000
Corpus ID: 83036251
Drug Discovery. Measurement of Drug Affinity. Efficacy. Pharmacological Assays Used in Screening for Therapeutic Ligands. Finding…
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Review
1997
Review
1997
Carbohydrate-based combinatorial libraries
M. Sofia
Molecular diversity
1997
Corpus ID: 42986072
Carbohydrate-based combinatorial libraries are tremendously valuable for studying the role of sugars in biology and for expanding…
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