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Small Molecule Libraries

Known as: chemical library, Libraries, Small Molecule, Libraries, Chemical 
Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening… 
National Institutes of Health

Related topics

Related topics

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High-Throughput Screening Assaysaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Medicinal chemistry as a conduit for the modulation of quorum sensing.
The evolutionary development of bacterial cell-to-cell communication, a process termed “quorum sensing” (QS), enabled coordinated… 
Review
2007
Review
2007
Strategies for developing protein tyrosine phosphatase inhibitors.
Review
2004
Review
2004
Exploring the chemogenomic knowledge space with annotated chemical libraries.
Review
2002
Review
2002
Optical barcoding of colloidal suspensions: applications in genomics, proteomics and drug discovery.
The enormous amount of information generated through sequencing of the human genome has increased demands for more economical and… 
2002
2002
Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity.
2002
2002
Discriminant and quantitative PLS analysis of competitive CYP2C9 inhibitors versus non-inhibitors using alignment independent GRIND descriptors
This study describes the use of alignment-independent descriptors for obtaining qualitative and quantitative predictions of the… 
2001
2001
Cellular biosensors for drug discovery.
Highly Cited
2000
Highly Cited
2000
Polymer-supported tetrafluorophenol: a new activated resin for chemical library synthesis.
A new tetrafluorophenol activated resin that facilitates the use of 19F NMR to quantitate loading is presented. This new resin… 
1998
1998
Solid-phase extraction on C18 silica as a purification strategy in the solution synthesis of a 1-thio-beta-D-galactopyranoside library.
Highly Cited
1996
Highly Cited
1996
Characterization of benzodiazepine "combinatorial" chemical libraries by on-line immunoaffinity extraction, coupled column HPLC-ion spray mass spectrometry-tandem mass spectrometry.
To characterize combinatorial chemical libraries of small drug compounds, an automated column switching system incorporating an… 
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