Skip to search formSkip to main contentSkip to account menu

Small Molecule Libraries

Known as: chemical library, Libraries, Small Molecule, Libraries, Chemical 
Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening… 
National Institutes of Health

Related topics

Related topics

4 relations
High-Throughput Screening Assaysaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
High-throughput sequencing for the identification of binding molecules from DNA-encoded chemical libraries.
Highly Cited
2009
Highly Cited
2009
Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds.
Nef is an HIV-1 accessory protein essential for AIDS progression and an attractive target for drug discovery. Lack of a catalytic… 
Review
2007
Review
2007
Strategies for developing protein tyrosine phosphatase inhibitors.
Review
2004
Review
2004
Exploring the chemogenomic knowledge space with annotated chemical libraries.
Highly Cited
2003
Highly Cited
2003
Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells.
Telomere maintenance is essential for the continued proliferation of dividing cells, and is implicated in chromosome stability… 
Review
2002
Review
2002
Optical barcoding of colloidal suspensions: applications in genomics, proteomics and drug discovery.
The enormous amount of information generated through sequencing of the human genome has increased demands for more economical and… 
2002
2002
Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity.
2002
2002
Discriminant and quantitative PLS analysis of competitive CYP2C9 inhibitors versus non-inhibitors using alignment independent GRIND descriptors
This study describes the use of alignment-independent descriptors for obtaining qualitative and quantitative predictions of the… 
Highly Cited
2000
Highly Cited
2000
Polymer-supported tetrafluorophenol: a new activated resin for chemical library synthesis.
A new tetrafluorophenol activated resin that facilitates the use of 19F NMR to quantitate loading is presented. This new resin… 
Highly Cited
1996
Highly Cited
1996
Characterization of benzodiazepine "combinatorial" chemical libraries by on-line immunoaffinity extraction, coupled column HPLC-ion spray mass spectrometry-tandem mass spectrometry.
To characterize combinatorial chemical libraries of small drug compounds, an automated column switching system incorporating an… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)