High Grade Lymphoma (neoplasm)

Known as: High-Grade Lymphoma, Lymphomas, High-Grade, High-Grade Lymphomas 
A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and intermediate-grade lymphoma.
National Institutes of Health

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7 relations
BIRC5 geneBIRC5 wt AlleleFRAT1 geneFRAT1 wt Allele
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Broader (1)

Lymphoma, Non-Hodgkin

Papers overview

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Highly Cited
2006
Highly Cited
2006
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
MicroRNAs (miRNAs) represent a newly discovered class of posttranscriptional regulatory noncoding small RNAs that bind to… (More)
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Highly Cited
2000
Highly Cited
2000
Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma.
Mantle cell lymphoma (MCL) is an aggressive neoplasm characterized by the deregulated expression of cyclin D1 by t(11;14). The… (More)
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Highly Cited
1995
Highly Cited
1995
BCL-2 gene family and the regulation of programmed cell death.
The BCL-2 gene was identified at the chromosomal breakpoint of t(14; 18)-bearing human follicular B cell lymphomas. BCL-2 proved… (More)
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Highly Cited
1994
Highly Cited
1994
p53 and bcl-2 expression in high-grade B-cell lymphomas: correlation with survival time.
B-cell high-grade lymphomas are heterogeneous in terms of histology, clinical presentation, treatment response and prognosis. As… (More)
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Highly Cited
1993
Highly Cited
1993
p53 mutation is associated with progression in follicular lymphomas.
The majority of low-grade follicular lymphomas will eventually transform to an aggressive intermediate, or high-grade lymphoma… (More)
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Highly Cited
1993
Highly Cited
1993
p53 mutations are associated with histologic transformation of follicular lymphoma.
The majority of low-grade non-Hodgkin's lymphomas (NHL) undergo clinical progression toward intermediate- and high-grade… (More)
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Highly Cited
1991
Highly Cited
1991
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
FOLLICULAR lymphoma, the most common human lymphoma, characteristically has a t(14;18) interchromosomal translocation1,2. It is… (More)
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Highly Cited
1988
Highly Cited
1988
Primary B cell lymphoma of the thyroid and its relationship to Hashimoto's thyroiditis.
Twenty-one cases were selected from 236 thyroidectomies with a diagnosis of Hashimoto's disease for detailed clinicopathologic… (More)
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Highly Cited
1986
Highly Cited
1986
Follicular lymphoma: prognostic factors for response and survival.
One hundred forty-eight patients with newly diagnosed follicular lymphoma were treated over a 12-year period. Twenty-two patients… (More)
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Highly Cited
1984
Highly Cited
1984
The natural history of initially untreated low-grade non-Hodgkin's lymphomas.
To learn more about the natural history of low-grade non-Hodgkin's lymphoma, we have studied 83 patients in whom the advanced… (More)
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