BIRC5 gene

Known as: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, EPR-1, survivin variant 3 alpha 
This gene regulates the apoptotic pathway by manipulation of the cell cycle. BIRC5 has been associated with several cancers.
National Institutes of Health

Papers overview

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2011
2011
BIRC5 (survivin) is one of the genes located on chromosome arm 17q in the region that is often gained in neuroblastoma. BIRC5 is… (More)
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2011
2011
Malignant pleural mesothelioma is an incurable, asbestos-associated cancer. Its incidence is rapidly increasing and survival… (More)
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2007
2007
Survivin is a good candidate for cancer immunotherapy since it is overexpressed in most common human cancers, poorly expressed in… (More)
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2006
2006
Previous studies have suggested that amplification of genes, notably the TOP2A gene, on chromosome arm 17q may be important for… (More)
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2006
2006
Despite advances in surgery, radiotherapy, and chemotherapy, the long-term survival rates with oral squamous cell carcinoma (OSCC… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Survivin, a member of the inhibitor of apoptosis (IAP) family, is not detected in normal adult tissues but is… (More)
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2002
2002
Survivin is a new member of the inhibitor of apoptosis family of anti-apoptotic proteins. It has been reported that survivin is… (More)
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2002
2002
Survivin is a new member of the inhibitor of apoptosis family of anti-apoptotic proteins. It has been reported that survivin is… (More)
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2002
2002
Malignant pleural mesothelioma is a rare and aggressive tumor characterized by rapid progression, late metastases, and poor… (More)
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Review
2001
Review
2001
Survivin has recently been identified as a novel inhibitor of apoptosis (IAP). Unlike other members of the IAP family, survivin… (More)
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