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Early indicators of prognosis in fulminant hepatic failure.
Long-term outcome of hepatitis C infection after liver transplantation.
After liver transplantation for HCV-related cirrhosis, persistent HCV infection can cause severe graft damage, and such damage is more frequent in patients infected with HCV genotype 1b than with other genotypes.
A longitudinal analysis of hepatitis C virus replication following liver transplantation.
BACKGROUND & AIMS The pathogenesis of graft injury in liver transplant recipients with recurrent hepatitis C virus (HCV) infection remains poorly understood. In this study, the relationship between…
Natural history and prognostic variables in primary sclerosing cholangitis.
Azathioprine for long-term maintenance of remission in autoimmune hepatitis.
Many patients with autoimmune hepatitis who have been in complete remission for at least one year with prednisolone and azathioprine can remain in remission with a higher dose of azathoprine alone, and two of these patients (both with pancytopenia) relapsed when the azathyprine was withdrawn; in the other two, remission was maintained with the resumption of prednisoone.
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection.
Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis.
DRB 1*0301 and DRB1*0401 are confirmed as the principal susceptibility alleles for type 1 autoimmune hepatitis, and the hypothesis that a lysine residue at position 71 of the DR beta-polypeptide chain may be the major risk factor is supported.
Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis
It is concluded that alleles associated with susceptibility to type 1 autoimmune hepatitis also influence its clinical features and prognosis.
Increased plasma tumor necrosis factor in severe alcoholic hepatitis.
- G. Bird, N. Sheron, A. Goka, G. Alexander, R. Williams
- MedicineAnnals of internal medicine
- 15 June 1990
Evaluation of the relation between tumor necrosis factor and plasma levels of endotoxin and interleukin-1 beta in patients with acute severe alcoholic hepatitis suggested that tumor Necrosis factor plays a role in the pathogenesis.
New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a
A new genotyping system based on PCR of the core region with genotype-specific PCR primers for the determination of hepatitis C virus genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a was developed and may be useful for large-scale determination of HCV genotypes in clinical studies.