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Long-term outcome of hepatitis C infection after liver transplantation.
TLDR
After liver transplantation for HCV-related cirrhosis, persistent HCV infection can cause severe graft damage, and such damage is more frequent in patients infected with HCV genotype 1b than with other genotypes. Expand
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group.
TLDR
Among patients with sickle cell disease, the acute chest syndrome is commonly precipitated by fat embolism and infection, especially community-acquired pneumonia, and among older patients and those with neurologic symptoms, the syndrome often progresses to respiratory failure. Expand
A longitudinal analysis of hepatitis C virus replication following liver transplantation.
BACKGROUND & AIMS The pathogenesis of graft injury in liver transplant recipients with recurrent hepatitis C virus (HCV) infection remains poorly understood. In this study, the relationship betweenExpand
Azathioprine for long-term maintenance of remission in autoimmune hepatitis.
TLDR
Many patients with autoimmune hepatitis who have been in complete remission for at least one year with prednisolone and azathioprine can remain in remission with a higher dose of azathoprine alone, and two of these patients (both with pancytopenia) relapsed when the azathyprine was withdrawn; in the other two, remission was maintained with the resumption of prednisoone. Expand
Pilot‐controlled trial of the extracorporeal liver assist device in acute liver failure
TLDR
Assessment of additive function for the device revealed an improvement in galactose elimination capacity after 6 hours of haemoperfusion, and better indices of prognosis will be required, in addition to those used to select for transplantation, if patients at an earlier stage of clinical deterioration are to be included in future studies. Expand
Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial.
TLDR
Acetylcysteine is safe and effective in fulminant hepatic failure after paracetamol overdose, and rates of deterioration and recovery of liver function were similar in the two groups. Expand
Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure
TLDR
Investigation of the ultrastructural appearance of brain capillaries by scanning electron microscopy found mainly cytotoxic mechanisms, with cellular swelling, and to a lesser extent vasogenic mechanism, with altered blood‐brain barrier permeability, appear to be involved in the cerebral edema of fulminant hepatic failure. Expand
Natural history and prognostic variables in primary sclerosing cholangitis.
TLDR
A prognostic model that should be valuable in the stratification of patients in clinical trials and in the timing of liver transplantation, particularly in those patients seen soon after presentation are produced. Expand
Bacterial and fungal infections after liver transplantation: An analysis of 284 patients
TLDR
A prospective study of bacterial and fungal infections after liver transplantation in 284 adults found patients with acute liver failure were more prone to bacterial, but not fungal, infection and no associations were found between infections and duration of surgery. Expand
Global trends in resistance to antituberculosis drugs. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance
TLDR
The survey expanded the survey conducted by the World Health Organization and the International Union against Tuberculosis and Lung Disease to assess trends in resistance to antituberculosis drugs in countries on six continents and identified areas with a high prevalence of multidrug-resistant tuberculosis in such countries as China and Iran. Expand
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