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Heterogeneous-Nuclear Ribonucleoprotein Group A-B

Known as: Type A B hnRNP Proteins, A B Family hnRNP Proteins, hnRNP A B Proteins 
A class of closely related heterogeneous-nuclear ribonucleoproteins of approximately 34-40 kDa in size. Although they are generally found in the… 
National Institutes of Health

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17 relations
HNRNPAB geneIn BloodProcess of secretionagonists

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HNRPA3 protein, humanHNRPAB protein, humanHnrpab protein, mouseheterogeneous nuclear ribonucleoprotein A2-B1

Papers overview

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Highly Cited
2017
Highly Cited
2017
The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes
G-quadruplexes are four-stranded conformations of nucleic acids that act as cellular epigenetic regulators. A dynamic G… 
Highly Cited
2013
Highly Cited
2013
A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing
Adenosine to inosine deamination of RNA is widespread in metazoa. Inosines are recognized as guanosines and, therefore, this RNA… 
Highly Cited
2010
Highly Cited
2010
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.
Caspase-9 is involved in the intrinsic apoptotic pathway and suggested to play a role as a tumor suppressor. Little is known… 
Highly Cited
2007
Highly Cited
2007
Combinatorial Control of Signal-Induced Exon Repression by hnRNP L and PSF
ABSTRACT Cells can regulate their protein repertoire in response to extracellular stimuli via alternative splicing; however, the… 
Highly Cited
2003
Highly Cited
2003
Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) exonic splicing silencers (ESSs) inhibit production of certain spliced viral… 
Highly Cited
2002
Highly Cited
2002
Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins.
Pre-mRNP complexes were isolated from rat liver nuclei as 40S hnRNP particles, and actin-binding proteins were collected by DNase… 
Highly Cited
2000
Highly Cited
2000
The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation
Individual members of the serine-arginine (SR) and heterogeneous nuclear ribonucleoprotein (hnRNP) A/B families of proteins have… 
Highly Cited
2000
Highly Cited
2000
In Vitro Properties of the Conserved Mammalian Protein hnRNP D Suggest a Role in Telomere Maintenance
ABSTRACT Mammalian chromosomes terminate with a 3′ tail which consists of reiterations of the G-rich repeat, d(TTAGGG). The… 
Highly Cited
1999
Highly Cited
1999
hnRNP A/B proteins are required for inhibition of HIV‐1 pre‐mRNA splicing
Splicing of the human immunodeficiency virus type 1 (HIV‐1) pre‐mRNA must be inefficient to provide a pool of unspliced messages… 
Highly Cited
1999
Highly Cited
1999
Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms.
hnRNP A2/B1 proteins are among the most abundant pre-mRNA-binding proteins of vertebrates and structurally similar to hnRNP A1… 
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