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RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation
TLDR
Interestingly, the three proteins alter RNA editing in a substrate-specific manner that correlates with their RNA binding preferences, and different editing sites can be specifically altered in their editing pattern by changing the local RNP landscape. Expand
A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing
TLDR
A two-stage in vivo editing screen aimed to isolate enhancers of editing was successfully employed to identify DSS1/SHFM1, the RNA binding protein hnRNP A2/B1 and a 3′ UTR as enhancer of editing. Expand
Transcript Diversification in the Nervous System: A to I RNA Editing in CNS Function and Disease Development
TLDR
The mechanisms of RNA editing are described and target mRNAs of editing that are functionally relevant to normal and aberrant CNS activity are focused on. Expand
A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability
TLDR
Key roles played by NAT lncRNAs in regulating post-transcriptional gene expression of key oncogenic or tumor suppressor genes, thereby contributing to TNBC progression are demonstrated. Expand
Increased expression levels of Syntaxin 1A and Synaptobrevin 2/Vesicle-Associated Membrane Protein-2 are associated with the progression of bladder cancer
TLDR
Findings suggest that elevated expression of STX1A and VAMP2 might have caused the abnormal progression and invasion of cancer cells leading to the transformation of cells into high-grade tumor in bladder cancer. Expand
Biosorption of arsenic through bacteria isolated from Pakistan
TLDR
The bacterial biomass generated from AT-01 strain was able to efficiently remove arsenic with 98% efficiency and shows the potential of high arsenic-resistant bacteria for efficient arsenic removal. Expand
Is atomic rearrangement of type IV PHA synthases responsible for increased PHA production?
TLDR
In silico study verifies that the close proximity between SH group of Cys and NH2 group of His in phaC subunit of type IV PHA synthases can be crucial for synthesis of scl-PHA. Expand
HriGFP Novel Flourescent Protein: Expression and Applications
TLDR
This study implies that HriGFP can act as a biosensor for detecting harmful carcinogenic pesticide like methyl parathion in water resources in the vicinity of heavily pesticide impregnated agricultural lands and heavy metal contaminated water bodies around industrial areas. Expand
LncRNA-mediated regulation of SOX9 expression in basal sub-type breast cancer cells.
TLDR
The results unearth tumor-promoting activities of a nuclear lncRNA linc02095 by facilitating the expression of key oncogenic transcription factor in BC. Expand
Capillary-Driven Flow Microfluidics Combined with Smartphone Detection: An Emerging Tool for Point-of-Care Diagnostics
TLDR
The capabilities of capillary-driven flow devices have not been fully exploited in developing POC diagnostics, especially for antimicrobial resistance studies in clinical settings, and the purpose of this review is to open up this field of microfluidics to the ever-expanding microfluodic-based scientific community. Expand
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