Heterochromatin

Known as: Heterochromatin [Chemical/Ingredient], Heterochromatins 
A tightly packed area of chromatin that may function to protect chromosome integrity and regulate gene expression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1942-2017
020040019422016

Papers overview

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Review
2016
Review
2016
Genome architecture is shaped by gene-rich and repeat-rich regions also known as euchromatin and heterochromatin, respectively… (More)
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Highly Cited
2008
Highly Cited
2008
Ataxia Telangiectasia Mutated (ATM) signaling is essential for the repair of a subset of DNA double-strand breaks (DSBs); however… (More)
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Highly Cited
2004
Highly Cited
2004
RNA interference (RNAi) is a widespread silencing mechanism that acts at both the posttranscriptional and transcriptional levels… (More)
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Highly Cited
2004
Highly Cited
2004
Histone lysine methylation is a central modification to mark functionally distinct chromatin regions. In particular, H3-K9… (More)
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Highly Cited
2004
Highly Cited
2004
Heterochromatin has been defined as deeply staining chromosomal material that remains condensed in interphase, whereas… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Histone H3 lysine 9 (H3-K9) methylation and DNA methylation are characteristic hallmarks of mammalian heterochromatin… (More)
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Highly Cited
2002
Highly Cited
2002
The higher-order assembly of chromatin imposes structural organization on the genetic information of eukaryotes and is thought to… (More)
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Highly Cited
2001
Highly Cited
2001
Histone H3 lysine 9 methylation has been proposed to provide a major "switch" for the functional organization of chromosomal… (More)
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Highly Cited
1997
Highly Cited
1997
We have generated and characterized a novel site-specific antibody highly specific for the phosphorylated form of the amino… (More)
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Highly Cited
1997
Highly Cited
1997
Ikaros proteins are required for normal T, B, and NK cell development and are postulated to activate lymphocyte-specific gene… (More)
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