Centric heterochromatin

Known as: centromeric heterochromatin, pericentric heterochromatin 
Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. [PMID… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
In eukaryotes, Suv39h H3K9 trimethyltransferases are required for pericentric heterochromatin formation and function. In early… (More)
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Highly Cited
2005
Highly Cited
2005
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21-25-nt-long species responsible for sequence-specific RNA… (More)
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Highly Cited
2004
Highly Cited
2004
Histone lysine methylation is a central modification to mark functionally distinct chromatin regions. In particular, H3-K9… (More)
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Review
2004
Review
2004
Heterochromatin maintenance is crucial for the clonal inheritance of cell identity, to ensure the proper segregation of… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Histone H3 lysine 9 (H3-K9) methylation and DNA methylation are characteristic hallmarks of mammalian heterochromatin… (More)
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Highly Cited
2002
Highly Cited
2002
Post-translational modification of histone tails is thought to modulate higher-order chromatin structure. Combinations of… (More)
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Highly Cited
2002
Highly Cited
2002
Covalent modification of histone tails is crucial for transcriptional regulation, mitotic chromosomal condensation, and… (More)
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Highly Cited
2001
Highly Cited
2001
Histone H3 lysine 9 methylation has been proposed to provide a major "switch" for the functional organization of chromosomal… (More)
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Highly Cited
2001
Highly Cited
2001
Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it mediates gene silencing. The chromo domain of HP1… (More)
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Highly Cited
2001
Highly Cited
2001
Histone modifications might act to mark and maintain functional chromatin domains during both interphase and mitosis. Here we… (More)
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