Hemojuvelin

Known as: Hemochromatosis Type 2 Protein, RGM Domain Family Member C, Repulsive Guidance Molecule C 
Hemojuvelin (426 aa, ~45 kDa) is encoded by the human HFE2 gene. This protein plays a role in both iron metabolism and bone morphogenetic protein… (More)

Topic mentions per year

Topic mentions per year

2004-2018
024620042018

Papers overview

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2012
2012
Hemojuvelin (HJV) and matriptase-2 (MT2) are co-expressed in hepatocytes, and both are essential for systemic iron homeostasis… (More)
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2011
2011
The adipose tissue may play an active role in systemic iron regulation and this role may be determinant in obese patients. Indeed… (More)
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2010
2010
BACKGROUND Hemojuvelin, a critical regulator of iron homeostasis, is involved in the regulation of hepcidin expression and iron… (More)
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2010
2010
Hemojuvelin (HJV) is an important regulator of iron metabolism. Membrane-anchored HJV up-regulates expression of the iron… (More)
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Highly Cited
2008
Highly Cited
2008
The liver peptide hepcidin regulates iron absorption and recycling. Hemojuvelin (HJV) has a key role in hepcidin regulation, and… (More)
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Highly Cited
2008
Highly Cited
2008
Hemojuvelin (HJV) is a coreceptor for bone morphogenetic protein (BMP) signaling that regulates hepcidin expression and iron… (More)
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Highly Cited
2007
Highly Cited
2007
Hemojuvelin (HJV), encoded by the gene HFE2, is a critical upstream regulator of hepcidin expression. Hepcidin, the central iron… (More)
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2007
2007
PURPOSE To prospectively analyze hepcidin, hemojuvelin, and ferroportin-1 expression after x-irradiation of rat liver and… (More)
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Highly Cited
2006
Highly Cited
2006
Hepcidin is a key regulator of systemic iron homeostasis. Hepcidin deficiency induces iron overload, whereas hepcidin excess… (More)
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Highly Cited
2005
Highly Cited
2005
Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing… (More)
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