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Hemojuvelin

Known as: Hemochromatosis Type 2 Protein, RGM Domain Family Member C, Repulsive Guidance Molecule C 
Hemojuvelin (426 aa, ~45 kDa) is encoded by the human HFE2 gene. This protein plays a role in both iron metabolism and bone morphogenetic protein… Expand
National Institutes of Health

Papers overview

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2014
2014
The first cell lineage determination in embryos takes place when two cell populations are set apart, each differentiating into… Expand
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2013
2013
HJV (haemojuvelin) plays a key role in iron metabolism in mammals by regulating expression of the liver-derived hormone hepcidin… Expand
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2011
2011
Iron homeostasis is a tightly regulated process that is maintained by several key factors that ensure proper iron distribution… Expand
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2010
2010
Inactivating mutations in hemojuvelin/repulsive guidance molecule c (HJV/RGMc) cause juvenile hemochromatosis (JH), a rapidly… Expand
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2010
2010
Repulsive guidance molecule c (RGMc; gene symbol: Hfe2) plays a critical role in iron metabolism. Inactivating mutations cause… Expand
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2008
2008
Juvenile hemochromatosis is a severe and rapidly progressing hereditary disorder of iron overload, and it is caused primarily by… Expand
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2007
2007
Genetic iron overload, or hemochromatosis, can be caused by mutations in HFE, hemojuvelin, and hepcidin genes. Hepcidin, a… Expand
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2006
2006
The recently discovered repulsive guidance molecule c (RGMc or hemojuvelin) gene encodes a putative glycosylphosphatidylinositol… Expand
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