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Hemojuvelin

Known as: Hemochromatosis Type 2 Protein, RGM Domain Family Member C, Repulsive Guidance Molecule C 
Hemojuvelin (426 aa, ~45 kDa) is encoded by the human HFE2 gene. This protein plays a role in both iron metabolism and bone morphogenetic protein… 
National Institutes of Health

Papers overview

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2014
2014
The first cell lineage determination in embryos takes place when two cell populations are set apart, each differentiating into… 
2013
2013
HJV (haemojuvelin) plays a key role in iron metabolism in mammals by regulating expression of the liver-derived hormone hepcidin… 
2011
2011
Iron homeostasis is a tightly regulated process that is maintained by several key factors that ensure proper iron distribution… 
2010
2010
Inactivating mutations in hemojuvelin/repulsive guidance molecule c (HJV/RGMc) cause juvenile hemochromatosis (JH), a rapidly… 
Highly Cited
2008
Highly Cited
2008
Juvenile hemochromatosis is a severe and rapidly progressing hereditary disorder of iron overload, and it is caused primarily by… 
2007
2007
Genetic iron overload, or hemochromatosis, can be caused by mutations in HFE, hemojuvelin, and hepcidin genes. Hepcidin, a… 
Highly Cited
2006
Highly Cited
2006
The recently discovered repulsive guidance molecule c (RGMc or hemojuvelin) gene encodes a putative glycosylphosphatidylinositol… 
2006
2006
The recently discovered repulsive guidance molecule c gene (RGMc; also known as HJV) encodes a putative…