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Hemoglobin H Disease
Known as:
HEMOGLOBIN H DISEASE, DELETIONAL
, ALPHA-THALASSEMIA, HEMOGLOBIN H TYPE
, Hemoglobin H
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A form of alpha thalassemia that results from reduced protein production from three of the four alpha-globin genes. Clinically it is characterized by…
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National Institutes of Health
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Related topics
Related topics
3 relations
Hematopoietic and Lymphoid Cell
Hematopoietic and Lymphoid Tissue
Broader (1)
alpha-Thalassemia
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
CFD model of ITER CICC. Part VI: Heat and mass transfer between cable region and central channel
R. Zanino
,
S. Giors
,
L. Richard
2010
Corpus ID: 54694668
2003
2003
The place of capillary electrophoresis techniques in screening for haemoglobinopathies
B. Gulbis
,
B. Fontaine
,
F. Vertongen
,
F. Cotton
Annals of Clinical Biochemistry
2003
Corpus ID: 19817369
Background: Capillary zone electrophoresis (CZE) methods are new laboratory diagnostic tools. The screening of haemoglobin (Hb…
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2000
2000
Molecular characterization and PCR detection of a deletional HPFH: Application to rapid prenatal diagnosis for compound heterozygotes of this defect with β‐thalassemia in a Chinese family
Xiang-min Xu
,
Zhi-qin Li
,
Zhong-ying Liu
,
X. Zhong
,
Yong-zhong Zhao
,
Q. Mo
American journal of hematology/oncology
2000
Corpus ID: 40494345
Hereditary persistence of fetal hemoglobin (HPFH) is one of the hemoglobinopathies in which the fetal γ‐globin genes remain…
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1999
1999
Human bleomycin hydrolase binds ribosomal proteins.
R. Koldamova
,
I. Lefterov
,
M. Disabella
,
C. Almonte
,
Simon C Watkins
,
J. Lazo
Biochemistry
1999
Corpus ID: 7797101
Bleomycin hydrolase (BH) is a cysteine proteinase that inactivates the anticancer drug bleomycin. Yeast BH forms a homohexameric…
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1998
1998
Essential binding and functional domains of human bleomycin hydrolase.
R. Koldamova
,
I. Lefterov
,
V. Gadjeva
,
J. Lazo
Biochemistry
1998
Corpus ID: 8801420
Bleomycin hydrolase (BH) is unusual among cysteine proteinases because it appears to form multihomomeric structures, inactivates…
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1998
1998
An evolutionarily conserved cysteine protease, human bleomycin hydrolase, binds to the human homologue of ubiquitin-conjugating enzyme 9.
R. Koldamova
,
I. Lefterov
,
M. Disabella
,
J. Lazo
Molecular Pharmacology
1998
Corpus ID: 2272861
Bleomycin hydrolase (BH) is a highly conserved cysteine proteinase that deamidates and inactivates the anticancer drug bleomycin…
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1998
1998
Binding of dihydroartemisinin to hemoglobin H: role in drug accumulation and host-induced antimalarial ineffectiveness of alpha-thalassemic erythrocytes.
P. Vattanaviboon
,
Prapon Wilairat
,
Yongyuth Yuthavong
Molecular Pharmacology
1998
Corpus ID: 6909758
Dihydroartemisinin and other artemisinin derivatives are relatively ineffective against Plasmodium falciparum infecting alpha…
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1995
1995
Optimizing the Detection of Hemoglobin H Disease
R. Hall
,
J. Haga
,
C. G. Guerra
,
S. Castleberry
,
J. R. Hickman
1995
Corpus ID: 75283598
Hemoglobin (Hb) H disease is a mild to severe chronic hemolytic anemia. The disease most commonly results from an absence of…
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Highly Cited
1985
Highly Cited
1985
Plasmodium falciparum in vitro: diminished growth in hemoglobin H disease erythrocytes.
Titus C. Ifediba
,
Arnold Stern
,
Amal Ibrahim
,
Ronald
,
Rieder
Blood
1985
Corpus ID: 35724561
Studies of the ability of Plasmodium falciparum to grow in vitro in the red blood cells of subjects with certain beta-thalassemia…
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1984
1984
Hemoglobin inclusions in heterozygous alpha-thalassemia according to their alpha-globin genotype.
R. Galanello
,
E. Paglietti
,
M. Melis
,
L. Giagu
,
A. Cao
Acta Haematologica
1984
Corpus ID: 46801987
In this study we have correlated the presence/absence of rare red blood cells with HbH inclusions with the alpha-globin genotype…
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