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alpha-Thalassemia

Known as: alpha-Thalassemias, Thalassemia alpha, Hemoglobin H Disease 
A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death… Expand
National Institutes of Health

Papers overview

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Review
2009
Review
2009
The thalassemias are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the… Expand
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Highly Cited
2007
Highly Cited
2007
HbVar (http://globin.bx.psu.edu/hbvar) is a locus-specific database (LSDB) developed in 2001 by a multi-center academic effort to… Expand
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Highly Cited
2005
Highly Cited
2005
The average results of some laboratory measurements, including the hemoglobin, mean corpuscular volume (MCV), serum transferrin… Expand
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Review
2005
Review
2005
Thalassemia is a growing global public health problem with an estimated 900,000 births of clinically significant thalassemia… Expand
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Highly Cited
2004
Highly Cited
2004
High frequency of erythrocyte (red blood cell [RBC]) genetic disorders such as sickle cell trait, thalassemia trait, homozygous… Expand
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Highly Cited
2003
Highly Cited
2003
Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on… Expand
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Highly Cited
2000
Highly Cited
2000
Alpha-thalassemia is very common throughout all tropical and subtropical regions of the world. In Southeast Asia and the… Expand
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Highly Cited
2000
Highly Cited
2000
We describe a sensitive, reliable and reproducible method, based on three multiplex PCR assays, for the rapid detection of seven… Expand
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Acute episodes of pain are the principal symptom of sickle cell disease, but little is known about the… Expand
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Highly Cited
1982
Highly Cited
1982
Patients with homozygous sickle-cell disease may be homozygous for alpha-thalassemia 2 (alpha-/alpha-), may be heterozygous for… Expand
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