alpha-Thalassemia

Known as: alpha-Thalassemias, Thalassemia alpha, Hemoglobin H Disease 
A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
05010019572017

Papers overview

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Highly Cited
2007
Highly Cited
2007
HbVar (http://globin.bx.psu.edu/hbvar) is a locus-specific database (LSDB) developed in 2001 by a multi-center academic effort to… (More)
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Highly Cited
2005
Highly Cited
2005
The average results of some laboratory measurements, including the hemoglobin, mean corpuscular volume (MCV), serum transferrin… (More)
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Highly Cited
2005
Highly Cited
2005
Although the alpha+ thalassemias almost certainly confer protection against death from malaria, this has not been formally… (More)
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Highly Cited
2004
Highly Cited
2004
High frequency of erythrocyte (red blood cell [RBC]) genetic disorders such as sickle cell trait, thalassemia trait, homozygous… (More)
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Highly Cited
2000
Highly Cited
2000
We describe a sensitive, reliable and reproducible method, based on three multiplex PCR assays, for the rapid detection of seven… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Acute episodes of pain are the principal symptom of sickle cell disease, but little is known about the… (More)
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Highly Cited
1982
Highly Cited
1982
We studied 47 patients with sickle-cell anemia to determine the effect of alpha-thalassemia on the severity of their hemolytic… (More)
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Highly Cited
1982
Highly Cited
1982
Patients with homozygous sickle-cell disease may be homozygous for alpha-thalassemia 2 (alpha-/alpha-), may be heterozygous for… (More)
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Highly Cited
1980
Highly Cited
1980
We report the isolation of a cluster of four alpha-like globin genes from a bacteriophage lambda library of human DNA (Lawn et al… (More)
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1969
1969
Whole blood samples of patients with various forms of alpha thalassemia including hemoglobin H disease, alpha thalassemia trait… (More)
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