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Helicobacter hepaticus

A species of HELICOBACTER that colonizes the CECUM and COLON of several strains of MICE, and is associated with HEPATITIS and carcinogenesis.
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Progression of Chronic Hepatitis and Preneoplasia in Helicobacter hepaticus-Infected A/JCr Mice
Helicobacter hepaticus infection induces sustained inflammation and carcinoma of the liver in A/JCr mice, and serves as a model… 
2003
2003
Analysis of Gene Expression in Ceca of Helicobacter hepaticus-Infected A/JCr Mice before and after Development of Typhlitis
ABSTRACT The inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the… 
Highly Cited
2000
Highly Cited
2000
Cytolethal Distending Toxin Sequence and Activity in the Enterohepatic Pathogen Helicobacter hepaticus
ABSTRACT Little is known about the molecular pathogenesis of hepatitis and enterocolitis caused by enterohepatic Helicobacter… 
Highly Cited
2000
Highly Cited
2000
Monitoring sentinel mice for Helicobacter hepaticus, H rodentium, and H bilis infection by use of polymerase chain reaction analysis and serologic testing.
BACKGROUND AND PURPOSE Natural infection of research mice with enterohepatic Helicobacter spp. is common and may confound… 
Review
1999
Review
1999
Pathology, diagnosis and epidemiology of the rodent Helicobacter infection.
1998
1998
Comparison of Methods of IdentifyingHelicobacter hepaticus in B6C3F1 Mice Used in a Carcinogenesis Bioassay
ABSTRACT In a long-term rodent bioassay evaluating the carcinogenicity of triethanolamine, there was equivocal evidence of… 
Highly Cited
1997
Highly Cited
1997
Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450 isoforms in hepatitis of mice infected with Helicobacter hepaticus.
A recently discovered bacterium, Helicobacter hepaticus, infects the intrahepatic bile canaliculi of mice, causing a severe… 
Highly Cited
1995
Highly Cited
1995
Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay
The identification of a new murine pathogen, Helicobacter hepaticus, and its association with chronic active hepatitis and liver… 
Highly Cited
1995
Highly Cited
1995
Diagnostic assay for Helicobacter hepaticus based on nucleotide sequence of its 16S rRNA gene
Conserved primers were used to PCR amplify 95% of the Helicobacter hepaticus 16S rRNA gene. Its sequence was determined and… 
1995
1995
Use of antibiotics to prevent hepatitis and typhlitis in male scid mice spontaneously infected with Helicobacter hepaticus.
The use of antibiotic combinations to prevent acute and progressive chronic hepatitis and proliferative typhlitis associated with… 
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