Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
- C. Baker, W. Phelps, V. Lindgren, M. Braun, M. Gonda, P. Howley
- BiologyJournal of Virology
- 1 April 1987
Transcription analysis revealed expression of the HPV-16 genome in each of these two cervical carcinoma cell lines, albeit at significantly different levels, and preliminary mapping of the viral RNA with subgenomic strand-specific probes indicated that viral transcription appeared to be derived primarily from the E6 and E7 ORFs.
Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS.
- J. Schüpbach, M. Popovič, R. Gilden, M. Gonda, M. Sarngadharan, R. Gallo
- Biology, MedicineScience
- 4 May 1984
Another subgroup of HTLV, designated HTLV-III, has now been isolated from many patients with AIDS and pre-AIDS and is shown to be a true member of the HTLV family.
Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species.
A new species of Helicobacter is reported that selectively and persistently colonizes the hepatic bile canaliculi of mice, causing a morphologically distinctive pattern of chronic, active hepatitis and associated with a high incidence of hepatocellular neoplasms in infected animals.
Nucleotide sequence and genome organization of biologically active proviruses of the bovine immunodeficiency-like virus.
- K. Garvey, M. Oberste, J. Elser, M. Braun, M. Gonda
- BiologyVirology
- 1 April 1990
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes
- R. Ellis, D. DeFeo, E. Scolnick
- BiologyNature
- 6 August 1981
Cloned probes from the Harvey and Kirsten strains of murine sarcoma virus encode enzymatically and serologically related p21 src proteins, which suggest that cellular p21 sarc genes constitute a divergent family of vertebrate genes that can regulate the growth of cells.
Simple, rapid, quantitative, syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody.
- P. Nara, W. Hatch, P. Fischinger
- BiologyAIDS Research and Human Retroviruses
- 1987
Results indicate that there are no detectable nonsyncytial variants in standard HIV-I stocks, andherent within this system is a flexible method for studying various kinetics of antibody/virus interactions, as well as blocking and interference studies with any candidate antiviral compounds.
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.
- M. Park, M. Dean, K. Kaul, M. Braun, M. Gonda, G. V. Vande Woude
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 1 September 1987
It is concluded that the MET protooncogene is a cell-surface receptor for an as-yet-unknown ligand that is most homologous with the human insulin receptor and v-abl.
Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus
- M. Gonda, M. Braun, M. J. Maaten
- BiologyNature
- 1987
The sequence data and serologic analyses together show that this bovine retrovirus is a novel lentivirus related to HIV and other lentiviruses, and it is proposed that this virus be tentatively named Bovine immunodeficiency-like virus (BIV) to reflect its genetic relationship and biological similarity to HIV.
Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma.
- A. Mamelak, S. Rosenfeld, M. Gonda
- MedicineJournal of Clinical Oncology
- 1 August 2006
Dosimetry and biodistribution from this first trial suggest that phase II studies of 131I-TM-601 are indicated and may have an antitumoral effect in patients with recurrent glioma.
Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.
- V. Karacostas, K. Nagashima, M. Gonda, B. Moss
- BiologyProceedings of the National Academy of Sciences…
- 1 November 1989
The production of noninfectious virus-like particles by expression vectors should be useful for biochemical studies and could provide a safe source of material for the development of vaccines.
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