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Heat Shock Protein Inhibitor

Known as: Hsp Inhibitor 
Any agent that inhibits functions of heat shock proteins (Hsp). Hsps are a group of homodimeric molecular chaperones that interact with a diverse… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Heat shock proteins 27 and 70 contribute to the protection of Schisandrin B against d-galactosamine-induced liver injury in mice.
Schisandrin B is a hepatoprotective component isolated from a traditional Chinese herb, Schisandra chinensis (Turcz.) Baill. This… 
2015
2015
From combinatorial chemistry to targeting nano-phototherapeutic agents
2015
2015
Palette of polarity-tunable halogenated bacteriochlorins for efficient photodynamic therapy in cellular and animal models
2014
2014
Stimulation of electroporation‐induced inward currents in glioblastoma cell lines by the heat shock protein inhibitor AUY922
Membrane electroporation (MEP) increases the electrical conductivity of the plasma membrane by addition of an external electrical… 
2013
2013
Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia
Abstract This phase I study was conducted to determine the maximum tolerated dose (MTD) and dose limiting toxicities (DLTs) of… 
2012
2012
The effect of KNK437, a heat shock protein inhibitor, on angiogenesis of endothelial cells
Aim: Hyperthermia is an effective therapy for cancer and tumor angiogenesis. However, the development of thermotolerance is an… 
2011
2011
Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways
Neurofibromatosis type 2 (NF2) is a genetic condition characterized by inactivation of the NF2 tumor suppressor gene and the… 
Review
2010
Review
2010
Suppression of herpes simplex virus 1 reactivation in a mouse eye model by cyclooxygenase inhibitor, heat shock protein inhibitor, and adenosine monophosphate
2006
2006
The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells
2005
2005
Attenuation of chronic thermotolerance by KNK437, a benzylidene lactam compound, enhances thermal radiosensitization in mild temperature hyperthermia combined with low dose-rate irradiation
Purpose: We investigated whether the attenuation of chronic thermotolerance by KNK437, a heat shock protein inhibitor, can modify… 
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