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- Publications
- Influence
Chemical kinectics : from molecular structure to chemical reactivity
- L. Arnaut, S. Formosinho, H. Burrows
- Chemistry
- 2007
1. Introduction 2. Reaction rate laws 3. Experimental methods 4. Rate constants and reaction orders 5. Collisions and molecular dynamics 6. Reactivity in thermalized systems 7. Structure-Reactivity… Expand
Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers
- J. Dąbrowski, Barbara Pucelik, +6 authors L. Arnaut
- Chemistry
- 15 October 2016
Abstract Applications of metalloporphyrins and related molecules have been extensively pursued in the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This review… Expand
Design of Pluronic-Based Formulation for Enhanced Redaporfin-Photodynamic Therapy against Pigmented Melanoma.
- Barbara Pucelik, L. Arnaut, G. Stochel, J. Dąbrowski
- Materials Science, Medicine
- ACS applied materials & interfaces
- 18 August 2016
The therapeutic outcome of photodynamic therapy (PDT) with redaporfin (a fluorinated sulfonamide bacteriochlorin, F2BMet or LUZ11) was improved using Pluronic-based (P123, F127) formulations. Neither… Expand
Photodynamic therapy (PDT) of cancer: from local to systemic treatment.
- J. Dąbrowski, L. Arnaut
- Medicine
- Photochemical & photobiological sciences…
- 30 September 2015
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and adequate use of both to trigger biological mechanisms that can rapidly destroy the primary tumour and provide… Expand
Mechanisms of singlet-oxygen and superoxide-ion generation by porphyrins and bacteriochlorins and their implications in photodynamic therapy.
- E. Silva, Carlos Serpa, +7 authors L. Arnaut
- Chemistry, Medicine
- Chemistry
- 9 August 2010
New halogenated and sulfonated bacteriochlorins and their analogous porphyrins are employed as photosensitizers of singlet oxygen and the superoxide ion. The mechanisms of energy and electron… Expand
Design of porphyrin-based photosensitizers for photodynamic therapy
- L. Arnaut
- Chemistry
- 2011
Abstract Porphyrin and metalloporphyrin derivatives are at the forefront of the photosensitizers currently investigated for the photodynamic therapy (PDT) of cancer. Earlier examples included various… Expand
Theoretical and Computational Models for Organic Chemistry
- S. Formosinho, I. Csizmadia, L. Arnaut
- Chemistry
- 1991
Proceedings of the NATO ASI held in Praia de Porto Novo, Portugal, August/September 1990. Ranges over the realm of theoretical and physical organic chemistry, from a novel potential energy surface… Expand
One Peptide Reveals the Two Faces of α-Helix Unfolding-Folding Dynamics.
- Catarina S H Jesus, P. Cruz, L. Arnaut, R. Brito, Carlos Serpa
- Chemistry, Medicine
- The journal of physical chemistry. B
- 20 March 2018
The understanding of fast folding dynamics of single α-helices comes mostly from studies on rationally designed peptides displaying sequences with high helical propensity. The folding/unfolding… Expand
Excited-state proton transfer reactions II. Intramolecular reactions
- S. Formosinho, L. Arnaut
- Chemistry
- 15 October 1993
Abstract Excited-state intramolecular proton transfer reactions are reviewed. Special emphasis is given to the intrinsic processes and to the mechanisms of proton transfers in relation to the nature… Expand
Photoacoustic Measurements of Porphyrin Triplet-State Quantum Yields and Singlet-Oxygen Efficiencies
- M. Piñeiro, A. Carvalho, Mariette M Pereira, A. R. Gonsalves, L. Arnaut, S. Formosinho
- Chemistry
- 2 November 1998
Photoacoustic calorimetry was used to measure the quantum yields of singlet molecular oxygen production by the triplet states of tetraphenylporphyrin (TPP), ZnTPP and CuTPP in toluene, yielding… Expand