HSP90AA1 wt Allele

Known as: Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1 wt Allele, HSP86, HSPCA 
Human HSP90AA1 wild-type allele is located in the vicinity of 14q32.33 and is approximately 59 kb in length. This allele, which encodes heat shock… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
020406019842017

Papers overview

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2010
2010
We reported previously that the stability of all mammalian phosphatidylinositol 3-kinase-related protein kinases (PIKKs) depends… (More)
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Highly Cited
2007
Highly Cited
2007
A primary pathologic component of Alzheimer's disease (AD) is the formation of neurofibrillary tangles composed of… (More)
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Highly Cited
2007
Highly Cited
2007
A comprehensive understanding of the cellular functions of the Hsp90 molecular chaperone has remained elusive. Although Hsp90 is… (More)
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Highly Cited
2006
Highly Cited
2006
The action of the molecular chaperone Hsp90 is essential for the activation and assembly of an increasing number of client… (More)
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Highly Cited
2005
Highly Cited
2005
Hsp90 is a molecular chaperone for many signal transducers and may influence evolution by releasing previously silent genetic… (More)
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2004
2004
The activity and structural integrity of the tumor suppressor protein p53 is of crucial importance for the prevention of cancer… (More)
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Highly Cited
2003
Highly Cited
2003
An evolutionary capacitor buffers genotypic variation under normal conditions, thereby promoting the accumulation of hidden… (More)
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Highly Cited
2002
Highly Cited
2002
Henoch-Schönlein Purpura nephritis (HSPN) has been extensively studied in children but, its natural history in adults is much… (More)
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2001
2001
Large peptidyl-prolyl cis/trans isomerases (PPIases) are important components of the Hsp90 chaperone complex. In mammalian cells… (More)
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Highly Cited
1999
Highly Cited
1999
Genetic screens in Drosophila have identified p50(cdc37) to be an essential component of the sevenless receptor/mitogen-activated… (More)
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