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HRH2 protein, human

Known as: Gastric Receptor 1, H2R, Histamine-2 Receptor 
Histamine H2 receptor (359 aa, ~40 kDa) is encoded by the human HRH2 gene. This protein is involved in the regulation of gastric acid secretion… 
National Institutes of Health

Related topics

Related topics

12 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingHRH2 geneHRH2 wt Allele

Broader (1)

Histamine H2 Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Histamine H2 Receptor-Mediated Suppression of Intestinal Inflammation by Probiotic Lactobacillus reuteri
ABSTRACT Probiotics and commensal intestinal microbes suppress mammalian cytokine production and intestinal inflammation in… 
2015
2015
Important drug classes associated with potential drug–drug interactions in critically ill patients: highlights for cardiothoracic intensivists
BackgroundPatients in the intensive care unit (ICU) are more prone to drug–drug interactions (DDIs). The software and charts that… 
Highly Cited
2013
Highly Cited
2013
Histamine-2 Receptor Blockers Alter the Fecal Microbiota in Premature Infants
Objectives: Bacterial colonization is considered a major risk factor for necrotizing enterocolitis (NEC). The objective of the… 
Review
2011
Review
2011
Response of Regurgitation to Proton Pump Inhibitor Therapy in Clinical Trials of Gastroesophageal Reflux Disease
OBJECTIVES:The typical symptoms of gastroesophageal reflux disease (GERD) are heartburn and regurgitation. Extensive analysis has… 
Review
2009
Review
2009
Erratum: Overutilization of Proton Pump Inhibitors: A Review of Cost-Effectiveness and Risk in PPI
Erratum: Overutilization of Proton Pump Inhibitors: A Review of Cost-Effectiveness and Risk 
Review
2005
Review
2005
Histamine-2 receptor antagonists at night improve gastroesophageal reflux disease symptoms for patients on proton pump inhibitor therapy.
While night-time symptoms of gastroesophageal reflux disease (GERD) are common, considerable controversy exists regarding the use… 
Highly Cited
2001
Highly Cited
2001
1,8-Cineol, a Food Flavoring Agent, Prevents Ethanol-Induced Gastric Injury in Rats
This study investigated the gastroptrotective effect of 1,8-cineole (cineole) on ethanol-induced gastric mucosal damage in rats… 
Highly Cited
2001
Highly Cited
2001
Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.
It is unknown why the potencies and efficacies of long-chained guanidine-type histamine H2-receptor (H2R) agonists are lower at… 
Review
2000
Review
2000
Overuse of acid-suppressive therapy in hospitalized patients
OBJECTIVES:The aims of this study were 1) to determine the frequency of use and indications for prescription of acid-suppressive… 
Review
1991
Review
1991
Central nervous system reactions to histamine-2 receptor blockers.
PURPOSE To review the incidence, risk factors, pharmacology, and management of central nervous system reactions to histamine-2… 
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