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HMR1031
Known as:
HMR 1031
, HMR-1031
National Institutes of Health
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2004
2004
Pharmacoscintigraphic Comparison of HMR 1031, a VLA-4 Antagonist, in Healthy Volunteers Following Delivery Via a Nebulizer and a Dry Powder Inhaler
S. Rohatagi
,
S. Chapel
,
+8 authors
B. Jensen
American Journal of Therapeutics
2004
Corpus ID: 24443817
A pharmacoscintigraphic study was conducted to compare the dose deposition of HMR 1031 from the existing nebulizer formulation…
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2004
2004
Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists.
F. Crofts
,
S. Rohatagi
,
+12 authors
R. Clark
Birth defects research. Part B. Developmental and…
2004
Corpus ID: 23081098
BACKGROUND Integrins such as VLA-4 (Very late antigen 4, integrin alpha4beta1) play key roles in cell-cell interactions that are…
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2003
2003
Effect of Food on Pharmacokinetics of an Inhaled Drug: A Case Study with a VLA‐4 Antagonist, HMR1031
B. Shah
,
B. Jensen
,
Jie Zhang
,
T. Hunt
,
S. Rohatagi
Journal of clinical pharmacology
2003
Corpus ID: 25517613
HMR1031 is a potent and specific antagonist of the integrin VLA‐4 (α4β1) binding to vascular cell adhesion molecule‐1 (VCAM‐1…
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