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Different embryo-fetal toxicity effects for three VLA-4 antagonists.
  • F. Crofts, M. Pino, +8 authors R. Clark
  • Biology, Medicine
  • Birth defects research. Part B, Developmental and…
  • 1 April 2004
BACKGROUND VLA-4 (Very late antigen 4, integrin alpha4beta1) plays an important role in cell-cell interactions that are critical for development. Homozygous null knockouts of the alpha4 subunit ofExpand
Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists.
BACKGROUND Integrins such as VLA-4 (Very late antigen 4, integrin alpha4beta1) play key roles in cell-cell interactions that are critical for development. Homozygous null knockouts of the VLA-4Expand
PROCESS FOR THE PREPARATION OF ISOFLAVONES BACKGROUND OF THE INVENTION
Sekizaki, H., et al., Studies on Zoospore Attracting Activity. II. Synthesis of Isoflavones and Their Activity to Aphano myces euteiches Zoospore. Biol Pharm Bull. 16:698 (1993). Miles, C.O., et al.,Expand