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HMR 1098

Known as: HMR-1098 
National Institutes of Health

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Benzamides

Papers overview

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2011
2011
HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels.
2008
2008
Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion.
Previous studies in our laboratory suggest that an acute inhibition of glycogen synthase kinase 3 (GSK3) by SB-216763 (SB21) is… 
Highly Cited
2006
Highly Cited
2006
Isoflurane Produces Sustained Cardiac Protection after Ischemia–Reperfusion Injury in Mice
Background: Isoflurane reduces myocardial ischemia–reperfusion injury within hours to days of reperfusion. Whether isoflurane… 
2006
2006
Preconditioning modulates pulmonary endothelial dysfunction following ischemia-reperfusion injury in the rat lung: role of potassium channels.
2005
2005
A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart.
2005
2005
Reduced effectiveness of HMR 1098 in blocking cardiac sarcolemmal K(ATP) channels during metabolic stress.
2004
2004
Effect of the Cardioselective, Sarcolemmal KATP Channel Blocker HMR 1098 on Atrial Electrical Remodeling During Pacing-Induced Atrial Fibrillation in Dogs
AbstractPurpose: The progressive shortening of the atrial effective refractory period (ERP) during atrial fibrillation (AF) might… 
2003
2003
Sustained exogenous administration of Met5-enkephalin protects against infarction in vivo.
The opioid antagonist naloxone abolishes infarct limitation by myocardial ischemic preconditioning, suggesting that one or more… 
2002
2002
The Role of Mitochondrial and Sarcolemmal KATP Channels in Canine Ethanol-Induced Preconditioning In Vivo
Chronic consumption of small doses of ethanol protects myocardium from ischemic injury. We tested the hypothesis that… 
2001
2001
Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion
Abstract. It has been argued that activation of KATP channels in the sarcolemmal membrane of heart muscle cells during ischemia… 
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