HMGB1 Protein

Known as: p30, Heparin-Binding Protein, High Mobility Group Protein B1, SBP-1 
High mobility group protein B1 (215 aa, ~25 kDa) is encoded by the human HMGB1 gene. This protein is involved in the regulation of both chromatin… (More)

Topic mentions per year

Topic mentions per year

1976-2018
010020030019762018

Papers overview

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Review
2015
Review
2015
The high mobility group box 1 (HMGB1), which belongs to the subfamily of HMG-1/-2, is a highly conserved single peptide chain… (More)
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Review
2015
Review
2015
High mobility group box 1 (HMGB1) is a widely-expressed and highly-abundant protein that acts as an extracellular signal upon… (More)
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Highly Cited
2010
Highly Cited
2010
Autophagy clears long-lived proteins and dysfunctional organelles and generates substrates for adenosine triphosphate production… (More)
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Highly Cited
2008
Highly Cited
2008
High mobility group box 1 protein (HMGB1), originally characterized as a nuclear DNA-binding protein, has also been described to… (More)
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Highly Cited
2007
Highly Cited
2007
Increased concentrations of DNA-containing immune complexes in the serum are associated with systemic autoimmune diseases such as… (More)
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Highly Cited
2005
Highly Cited
2005
High-mobility group box 1 (HMGB1) is a nuclear factor that is released extracellularly as a late mediator of lethality in sepsis… (More)
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Highly Cited
2004
Highly Cited
2004
Immune responses against pathogens require that microbial components promote the activation of antigen-presenting cells (APCs… (More)
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Highly Cited
2003
Highly Cited
2003
Systemic inflammation because of sepsis results in endothelial cell activation and microvascular injury. High-mobility group… (More)
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Highly Cited
2002
Highly Cited
2002
HMGB1, a non-histone nuclear factor, acts extracellularly as a mediator of delayed endotoxin lethality, which raises the question… (More)
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Highly Cited
1999
Highly Cited
1999
Endotoxin, a constituent of Gram-negative bacteria, stimulates macrophages to release large quantities of tumor necrosis factor… (More)
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