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HMGB1 Protein

Known as: p30, Heparin-Binding Protein, High Mobility Group Protein B1, SBP-1 
High mobility group protein B1 (215 aa, ~25 kDa) is encoded by the human HMGB1 gene. This protein is involved in the regulation of both chromatin… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in perspective with the emergence of… Expand
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Review
2011
Review
2011
A key question in immunology concerns how sterile injury activates innate immunity to mediate damaging inflammation in the… Expand
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Highly Cited
2010
Highly Cited
2010
This corrects the article DOI: 10.1038/nature00858 
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Highly Cited
2007
Highly Cited
2007
Increased concentrations of DNA-containing immune complexes in the serum are associated with systemic autoimmune diseases such as… Expand
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Highly Cited
2006
Highly Cited
2006
In response to bacterial endotoxin (e.g., LPS) or endogenous proinflammatory cytokines (e.g., TNF and IL-1beta), innate immune… Expand
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Review
2005
Review
2005
High-mobility group box 1 protein (HMGB1), which previously was thought to function only as a nuclear factor that enhances… Expand
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Highly Cited
2005
Highly Cited
2005
High-mobility group box 1 (HMGB1) is a nuclear factor that is released extracellularly as a late mediator of lethality in sepsis… Expand
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Highly Cited
2003
Highly Cited
2003
High Mobility Group 1 protein (HMGB1) is a chromatin component that, when leaked out by necrotic cells, triggers inflammation… Expand
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Highly Cited
2002
Highly Cited
2002
High mobility group 1 (HMGB1) protein is both a nuclear factor and a secreted protein. In the cell nucleus it acts as an… Expand
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Highly Cited
2002
Highly Cited
2002
HMGB1, a non-histone nuclear factor, acts extracellularly as a mediator of delayed endotoxin lethality, which raises the question… Expand
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