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HMGB1 Protein

Known as: p30, Heparin-Binding Protein, High Mobility Group Protein B1, SBP-1 
High mobility group protein B1 (215 aa, ~25 kDa) is encoded by the human HMGB1 gene. This protein is involved in the regulation of both chromatin… 
National Institutes of Health

Related topics

Related topics

22 relations
DNA RepairDNA Topology RegulationDNA-Binding ProteinsGenes, Regulator

Papers overview

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Highly Cited
2007
Highly Cited
2007
Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus
HMGB1 is a pro-inflammatory cytokine that together with TNF-α and IL-1β is involved in the pathogenesis of spontaneously… 
Highly Cited
1999
Highly Cited
1999
HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells.
Estrogen receptor (ER) toxicity has hampered the development of vertebrate cell lines stably expressing substantial levels of… 
Highly Cited
1998
Highly Cited
1998
Sp1-binding Elements in the Promoter of RAGE Are Essential for Amphoterin-mediated Gene Expression in Cultured Neuroblastoma Cells*
Receptor for AGE (RAGE) and the polypeptide amphoterin are highly expressed and co-localized in neurons of the developing central… 
Highly Cited
1997
Highly Cited
1997
High-mobility group (HMG) protein HMG-1 and TATA-binding protein-associated factor TAF(II)30 affect estrogen receptor-mediated transcriptional activation.
The estrogen receptor (ER) belongs to a family of ligand-inducible nuclear receptors that exert their effects by binding to cis… 
Highly Cited
1996
Highly Cited
1996
Localized DNA flexibility contributes to target site selection by DNA-bending proteins.
Certain DNA-binding proteins function as architectural elements by bending DNA. We have studied the binding of three such… 
Highly Cited
1989
Highly Cited
1989
Positive and negative transcriptional control by heme of genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae
Responses of the yeast genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase, HMG1 and HMG2, to in vivo changes in heme… 
Highly Cited
1983
Highly Cited
1983
ADP-ribosylation of chromosomal proteins and mouse mammary tumor virus gene expression. Glucocorticoids rapidly decrease endogenous ADP-ribosylation of nonhistone high mobility group 14 and 17…
Highly Cited
1979
Highly Cited
1979
Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells
Highly Cited
1979
Highly Cited
1979
Chromatin fractionation procedure that yields nucleosomes containing near-stoichiometric amounts of high mobility group nonhistone chromosomal proteins.
Initial results of an approach to the isolation of functionally active chromatin are described. Slight digestion of mouse myeloma… 
Highly Cited
1978
Highly Cited
1978
Immunological relatedness of high mobility group chromosomal proteins from calf thymus.
The non-histone proteins HMG-1, HMG-2, HMG-3, HMB-8, HMG-14, and HMG-17 (Goodwin, G. H., SANDERS, C., and Johns, E. W. (1973) Eur… 
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