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HMGA1b Protein

Known as: High Mobility Group Protein HMG Isoform HMG-Y, High Mobility Group AT-Hook Protein 1b, High Mobility Group AT-Hook 1b 
An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich regions of DNA. It is a truncated form of HMGA1a… 
National Institutes of Health

Related topics

Related topics

21 relations
AT-Hook MotifsDNA Topology RegulationDNA-Binding ProteinsGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Evidence That an HMGA1 Gene Variant Associates with Type 2 Diabetes, Body Mass Index, and High-Density Lipoprotein Cholesterol in a Hispanic-American Population
Abstract Background: High-mobility group AT-hook 1 (HMGA1) is an important regulator of the insulin receptor gene. We have… 
2013
2013
A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer
Lung cancer accounts for the highest number of cancer-related deaths worldwide. Early diagnosis significantly increases the… 
2011
2011
HMGA1-dependent and independent 7SK RNA gene regulatory activity
The small nuclear 7SK RNA negatively controls transcription by inactivating positive transcription elongation factor b (P-TEFb… 
2009
2009
Regulation of microRNA expression by HMGA1 proteins
The High Mobility Group proteins HMGA1 are nuclear architectural factors that play a critical role in a wide range of biological… 
2008
2008
High mobility group AT‐hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma
High mobility group AT‐hook 1 (HMGA1) proteins are architectural transcription factors that are overexpressed by pancreatic… 
Highly Cited
2004
Highly Cited
2004
HMGA1 Protein Overexpression in Human Breast Carcinomas
We measured, by immunohistochemistry, HMGA1 protein expression in 212 breast tissue specimens: 6 normal samples, 28 hyperplastic… 
2003
2003
High-mobility group A1 proteins are overexpressed in human leukaemias.
High-mobility group A (HMGA) proteins are non-histone nuclear proteins that bind DNA and several transcription factors. They are… 
Highly Cited
2003
Highly Cited
2003
High mobility group protein HMGA1 expression in breast cancer reveals a positive correlation with tumour grade.
Members of the HMGA protein (high mobility group protein A) family act as master switches of the chromatin structure by bending… 
Highly Cited
1994
Highly Cited
1994
Expression and cDNA cloning of human HMGI-C phosphoprotein.
The HMGI family contains three members: I, Y and I-C. HMGI and HMGY are alternative splicings of the same gene and are essential… 
1992
1992
Mass spectrometric analysis of the HMGY protein from Lewis lung carcinoma. Identification of phosphorylation sites.
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