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HIPK2 protein, human

Known as: homeodomain interacting protein kinase 2, human, Homeodomain-Interacting Protein Kinase 2, Homeodomain Interacting Protein Kinase 2 
Homeodomain-interacting protein kinase 2 (1198 aa, ~131 kDa) is encoded by the human HIPK2 gene. This protein plays a role in protein phosphorylation… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Carrier ProteinsProtein-Serine-Threonine Kinases
Cell Cycle ControlCell NucleusEnzyme GeneHIPK2 gene

Papers overview

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Highly Cited
2016
Highly Cited
2016
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
2013
2013
Differential expression of human homeodomain TGIFLX in brain tumor cell lines.
Glioblastoma is the most common and the most lethal primary brain cancer. This malignancy is highly locally invasive, rarely… 
Highly Cited
2011
Highly Cited
2011
Phosphorylation of TCF Proteins by Homeodomain-interacting Protein Kinase 2*
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic development… 
Review
2010
Review
2010
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important… 
Highly Cited
2006
Highly Cited
2006
Transcriptional Activation of the SALL1 by the Human SIX1 Homeodomain during Kidney Development*
SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors. SALL1 plays a… 
Highly Cited
2006
Highly Cited
2006
c-Jun NH2-terminal Kinase Promotes Apoptosis by Down-regulating the Transcriptional Co-repressor CtBP*
Genetic knock out of the transcriptional co-repressor carboxyl-terminal-binding protein (CtBP) in mouse embryonic fibroblasts… 
2005
2005
Desumoylation of homeodomain‐interacting protein kinase 2 (HIPK2) through the cytoplasmic‐nuclear shuttling of the SUMO‐specific protease SENP1
2005
2005
Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability.
2002
2002
HIPK2 associates with RanBPM.
Highly Cited
1999
Highly Cited
1999
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1.
Posttranslational modifications such as ubiquitination and phosphorylation play an important role in the regulation of cellular… 
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