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HI 443

Known as: HI-443, N'-(2-(2-thiophene)ethyl)-N'-(2-(5-bromopyridyl))thiourea 
National Institutes of Health

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PHI 443

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PyridinesThiourea
analogs & derivatives

Papers overview

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2007
2007
N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a Rationally Designed Non-Nucleoside Reverse Transcriptase Inhibitor Compound with Potent Anti-HIV Activity
Abstract The in vitro activity profile of N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (CAS 258340-15-7, HI-443) was… 
2007
2007
In vivo Pharmacokinetics, Metabolism, Toxicity, and Anti-HIV Activity of N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a Potent Non-nucleoside Inhibitor of HIV Reverse…
Summary N'-[2- (2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea (CAS 258340-15-7, HI-443) is a potent non-nucleoslde… 
2007
2007
Improved Oral Bioavailability of Anti-HIV Agent N'-[2-(2-Thiophene)ethyl]-NT-[2-(5-bromopyridyl)]-thiourea (HI-443) in a Novel Lipophilic Formulation
Summary N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (CAS 258340-15-7, HI-443) is a rationally designed non… 
2007
2007
Large-scale Synthesis of GMP Grade N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (HI-443), a New Anti-HIV Drug Candidate
Abstract The thiourea compound N'-[2-(2-thio-phene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (HI-443, CAS 258340-15-7), was found… 
2007
2007
In vivo Pharmacokinetics and Toxicity of a Novel Hydrophilic Oral Formulation of the Potent Non-Nucleoside Reverse Transcriptase Inhibitor Compound N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl…
Abstract The thiophene ethyl thiourea (TET) compound N'-[2-(2-thiophene) ethyl]-N'- [2-(5-bromopyridyl)]-thiourea (HI-443) is a… 
1999
1999
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.
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