Skip to search formSkip to main contentSkip to account menu

HERC2 gene

Known as: HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase 2 Gene, HECT DOMAIN AND RCC1-LIKE DOMAIN 2, p528 
This gene is involved in both protein ubiquitination and DNA damage repair.
National Institutes of Health

Related topics

Related topics

4 relations
DNA RepairHERC2P2 geneHERC2P4 geneUbiquitination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Proteomic investigations of human HERC2 mutants: Insights into the pathobiology of a neurodevelopmental disorder.
2018
2018
P528 Patients’ perspectives on switching from reference infliximab to CT-P13 biosimilar in patients with inflammatory bowel disease: A 12-month prospective observational cohort study
2017
2017
Co-factor-independent phosphoglycerate mutase of Leishmania donovani modulates macrophage signalling and promotes T-cell repertoires bearing epitopes for both MHC-I and MHC-II
SUMMARY Immunoactivation depends upon the antigen potential to modulate T-cell repertoires. The present study has enumerated the… 
2016
2016
Selected gene polymorphisms effect on skin and hair pigmentation in Polish children at the prepubertal age.
SUMMARY Background: Human pigmentation, similarly as many other biological features, changes in the course of post-natal… 
Highly Cited
2014
Highly Cited
2014
HERC2-USP20 axis regulates DNA damage checkpoint through Claspin
The DNA damage response triggers cell-cycle checkpoints, DNA repair and apoptosis using multiple post-translational modifications… 
2014
2014
The Histone H 2 A Deubiquitinase USP 16 Interacts with HERC 2 and Fine-tunes Cellular Response to DNA Damage *
Background: Protein factors that negatively regulate DNA damage-induced ubiquitin foci formation are less known. Results: USP16… 
2012
2012
RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells.
2010
2010
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Regulatory ubiquitylation is emerging as an important mechanism to protect genome integrity in cells exposed to DNA damage1–9… 
2009
2009
Ubiquitin ligases join the field of dietary restriction in C.elegans
Dietary restriction (DR) has been shown to robustly modulate organismal lifespan in multiple species. The powerful genetic tools… 
2008
2008
Specific Inhibition of Syk Is Sufficient to Disrupt Proliferation and Survival of Non-Hodgkin’s Lymphoma Cell Lines without Concomitant Inhibition of JAK.
Abstract Recent studies indicate that dual inhibition of the spleen tyrosine kinase (Syk) and Janus kinases (JAK) by agents such… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)