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HER2/Neu/cerbB2 Antagonists [MoA]

Known as: HER-2/Neu/cerbB2 Antagonists, HER2 Inhibitors, HER-2 Inhibitors 
National Institutes of Health

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14 ML pertuzumab 30 MG/ML Injectionado-trastuzumab emtansinepertuzumabtrastuzumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 3082: Deficient NOXA in HER2-amplified breast cancer drives kinase inhibitor resistance
The purpose of this study is the development of a novel combination therapy that targets HER2-amplified breast cancer. About one… 
2015
2015
Иммуногистохимическая диагностика гормоно-рецепторного статуса рака молочной железы с прогнозом основных направлений противоопухолевой лекарственной терапии
The data on the cost of immunohistochemical diagnosing of the hormone-receptor status and the diagnostic coverage of the women… 
2014
2014
Targeting HER2+ breast cancer: the TBK1/IKKε axis
HER2+ breast cancer (BC) is a highly aggressive subtype, affecting ~20% of BC patients. Current treatments include adjuvant or… 
Review
2014
Review
2014
Innovationen in der medikamentösen Therapie des Mammakarzinoms
ZusammenfassungHintergrundIn den vergangenen Jahren wurden bei den nichtzytostatischen Therapien deutliche Therapiefortschritte… 
2013
2013
Anti-Neoplastic Cytotoxicity of Gemcitabine-(C4-amide)-[anti-HER2/neu] in Combination with Griseofulvin against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3)
Introduction Gemcitabine is a pyrimidine nucleoside analog that becomes triphosphorylated and in this form it competitively… 
2013
2013
Expression of Molecular Markers in Tumours of Patients with Breast Cancer
The expression of transcription factor NF-κB (p50 and p65), ER, PR, Her2/neu, Ki-67, p53, Bcl-2 and E-cadherin in tumor tissue of… 
2011
2011
Molekularbiologische Analyse von Her2/neu-Nanostrukturen in unterschiedlichen Brustkrebszelllinien auf Gen- und Proteinebene basierend auf hochaufgelösten fluoreszenzmikroskopischen Darstellungen
Untersuchungen zur Her2/neu-Amplifikation und -Expression, die im Zusammenhang mit der Entstehung von Brustkrebs und seiner… 
2009
2009
Dual potency anti-HER2/neu and anti-EGFR anthracycline immunoconjugates in chemotherapeutic-resistant mammary carcinoma combined with cyclosporin A and verapamil P-glycoprotein inhibition
Immunoconjugates of epirubicin were synthesized with monoclonal antibodies against the epidermal growth factor receptors, HER2… 
2008
2008
Molekulare Pathogenese und Biologie des CUP-Syndroms
ZusammenfassungUnter „Cancer-of-unknown-primary“-Syndrom, kurz CUP-Syndrom, werden diejenigen Tumorerkrankungen zusammengefasst… 
Review
1995
Review
1995
Regulation of her2/neu gene-expression (review).
Transcriptional regulation of the HER2/neu protooncogene (also known as c-erbB2) has been the topic of many recent reports. The… 
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