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ado-trastuzumab emtansine
Known as:
T-DM1 cpd
, Trastuzumab emtansine
, Trastuzumab-MCC-DM1 Immunoconjugate
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An antibody-drug conjugate (ADC) consisting of the recombinant anti-epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab…
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National Institutes of Health
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Related topics
Related topics
15 relations
ADO-TRASTUZUMAB
Drug Allergy
HER2/Neu/cerbB2 Antagonists [MoA]
Mammary Neoplasms
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Broader (4)
Antibodies, Monoclonal, Humanized
Antineoplastic Agents
Maytansine
Tubulin Modulators
Narrower (3)
KADCYLA
PRO132365
huN901-DM1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract P6-17-02: Trastuzumab deruxtecan (DS-8201a) in subjects with HER2-low expressing breast cancer: Updated results of a large phase 1 study
S. Modi
,
J. Tsurutani
,
+13 authors
S. Takahashi
Poster Session Abstracts
2019
Corpus ID: 86741155
Background: HER2-targeted therapies have improved survival for advanced HER2-positive breast cancers (BC), but none have been…
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2016
2016
Final analysis of WSG-ADAPT HER2+/HR+ phase-II-trial - efficacy, safety and predictive markers for 12-weeks of neoadjuvant T-DM1 with or without endocrine therapy versus Trastuzumab plus endocrine…
M. Braun
,
O. Gluz
,
+15 authors
N. Harbecks
2016
Corpus ID: 80924710
2011
2011
MICROBIAL CONTAMINATION OF SOME HAWKED HERBAL PRODUCTS IN ADO-EKITI, NIGERIA
Oluyege J O Adelabu
2011
Corpus ID: 18878321
An investigation was conducted on the microbial con tamination of some herbal products hawked in Ado-Ekiti metropolis. Eight…
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2010
2010
Quantitative assessment of diagnostic markers and correlations with efficacy in two phase II studies of trastuzumab-DM1 (T-DM1) for patients (pts) with metastatic breast cancer (MBC) who had…
P. LoRusso
,
I. Krop
,
+7 authors
H. Rugo
2010
Corpus ID: 78233749
1016 Background: The antibody-drug conjugate T-DM1 has shown encouraging efficacy in two phase II studies (4258g and 4374g) for…
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2010
2010
Abstract P6-15-02: A Phase Ib Study Evaluating Safety, Tolerability, Pharmacokinetics (PK), and Activity of the Phosphoinositide-3 Kinase (PI3K) Inhibitor GDC-0941 in Combination with Trastuzumab-MCC…
I. Krop
,
A. Wolff
,
+7 authors
A. Storniolo
2010
Corpus ID: 76089939
Background: Aberrant activation of the PI3K pathway has been hypothesized to reduce the efficacy of trastuzumab-based therapy in…
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2005
2005
Egy országos, átnézetes, térbeli talajinformációs rendszer kiépítésének igénye, lehetősége és lépései
J. Szabó
,
L. Pásztor
,
Zs. Bakacsi
2005
Corpus ID: 110455601
A talajokra vonatkozo informacioigeny az utobbi evtizedekben erőteljesen megnovekedett, nem csak az agrarium reszeről. Az…
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Review
2005
Review
2005
Herder-Farmer Conflicts In The Dawa-Ganale River Basin Areas: The Case of Intra Clan Conflict Among The Degodia Somali of Dollo Ado District In The Somali Regional State of Ethiopia
Ahmed Ali
2005
Corpus ID: 135293366
Table o f Content…
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2004
2004
ENGELLİ ÇOCUKLARI OLAN ANABABALARIN ALGILADIKLARI STRES, SOSYAL DESTEK VE YAŞAM DOYUMLARININ İNCELENMESİ
Sema Kaner
2004
Corpus ID: 193891490
Bu arastirmanin amaci, yetersizligi olan cocuga sahip anne ve babalarin algiladiklari stres, sosyal destek ve yasam doyumlari…
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1994
1994
ENHANCED FUNCTIONAL PRESERVATION OF COLD‐STORED RAT HEART BY A NUCLEOSIDE TRANSPORT INHIBITOR1
X. Yang
,
Q. Zhu
,
M. Claydon
,
G. Hicks
,
T. Wang
Transplantation
1994
Corpus ID: 25742905
This study investigates the hypothesis that inhibition of nucleoside transport during hypothermic storage elevates tissue…
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1985
1985
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 8. Molecular dissections of carbocyclic 3-deazaadenosine as inhibitors of S-adenosylhomocysteine hydrolase.
D. Houston
,
E. Dolence
,
B. Keller
,
U. Patel-Thombre
,
R. Borchardt
Journal of Medicinal Chemistry
1985
Corpus ID: 35703629
A series of 9-(hydroxyalkyl)-3-deazaadenines, which are analogues of the carbocyclic derivative of 3-deazaadenosine (3-deaza-C…
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