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HER-2/neu intracellular domain protein

Known as: HER-2 ICD Peptide, HER2 Intracellular Domain, HER2 ICD 
The cytoplasmic domain or intracellular domain (ICD) of the HER2/neu protein that exhibits tyrosine kinase activity. Based on sensitization theory… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

erbB-2 Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Shed HER2 surrogacy evaluation in primary breast cancer patients: a study assessing tumor tissue HER2 expression at both extracellular and intracellular levels
Abstract The aim of the present study was to investigate serum HER2 extracellular domain (ECD) as a putative surrogate marker of… 
2016
2016
Abstract P2-11-03: Phase I/II randomized study of combination immunotherapy with or without polysaccharide krestin (PSK) concurrently with a HER2 ICD peptide-based vaccine in patients with stage IV…
Natural killer (NK) cell defects, commonly seen in metastatic breast cancer (MBC) lead to decrease in dendritic cell (DC… 
2016
2016
Abstract P3-07-06: Objective measurement of HER2 (ERBB2) intracellular and extracellular domain spatial co-localization stratifies benefit from adjuvant trastuzumab
Background: The ASCO/CAP guidelines consider chromogen-based immunohistochemistry (IHC) as the primary assay to determine HER2… 
2012
2012
Abstract 5577: HER2 cytoplasmic staining and penile cancer
BACKGROUND: Although rare in developed regions, penile carcinoma is a serious concern for undeveloped countries such as Brazil… 
2010
2010
HER-2/neu siRNA对人胶质瘤细胞株T98G侵袭性的抑制作用
目的 探讨人表皮生长因子受体-2（HER-2/neu）特异性siRNA对高表达HER-2/neu的人胶质瘤细胞株T98G侵袭性的影响及其机制.方法 用脂质体介导终质量浓度50 nmol/LHER-2/neu siRNA转染人胶质瘤细胞株T98G… 
2009
2009
Study of HER-2/neu Intracellular Domain Peptide-Based Vaccine Administered to Stage IV HER2 Positive Breast Cancer Patients Receiving Trastuzumab. Phase 2
Abstract : The primary purpose of this grant is to determine the relapse free survival benefit with locally advanced and stage IV… 
2004
2004
악성 근골격계 종양세서 CD117[c-kit]과 Her-2/neu 유전자 발현
목적: 본 연구는 악성 근골격계 종양에서 c-kit (CD117) 유전자 단백질 발현과 Her-2/neu… 
2004
2004
Discovery and development of CP-724714, a selective HER2 receptor tyrosine kinase inhibitor.
3122 Background: The HER2 (neu/erbB2) proto-oncogene has been linked to human malignancies including tumors of the breast, ovary… 
2003
2003
Induktion Her-2/neu spezifischer T-Zellen durch infizierte autologe dendritische Zellen mittels rekombinantem viralen Vektor MVA und Charakterisierung MVA infizierter DC's
Die intrinsische Aktivitat einiger Viren das Immunsystem zu aktivieren, wird sich fur derzeitige Strategien einer Immuntherapie… 
2000
2000
Sentinel-Lymphknotenbiopsie — Freie Themen
noklonalen (Ab-2 und Ab-3. Oncogene: CBll . Novocastra: TAB 250, Zymed; HER-2/neu. GSF Mdnchen) und 2 polyklonalen (A 8010, Oncor… 
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