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HDAC5 protein, human

Known as: Histone Deacetylase 5, NY-CO-9 protein, human, histone deacetylase 5, human 
Histone deacetylase 5 (1122 aa, ~122 kDa) is encoded by the human HDAC5 gene. This protein is involved in chromatin silencing, transcriptional… 
National Institutes of Health

Related topics

Related topics

14 relations
Chromatin Remodeling FactorDeacetylationEnzyme GeneEstrogen Receptor Regulation by CARM1 Pathway

Broader (1)

Histone Deacetylase

Papers overview

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Highly Cited
2012
Highly Cited
2012
Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib.
Highly Cited
2010
Highly Cited
2010
HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth
Purpose: Medulloblastomas are the most common malignant brain tumors in childhood. Survivors suffer from high morbidity because… 
Highly Cited
2008
Highly Cited
2008
Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells
Abstract:  We have reported the induction of glial cell line‐derived neurotrophic factor, a potent survival factor for… 
Highly Cited
2007
Highly Cited
2007
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
TLX is a transcription factor that is essential for neural stem cell proliferation and self-renewal. However, the molecular… 
Highly Cited
2007
Highly Cited
2007
Altered HDAC5 and CREB mRNA expressions in the peripheral leukocytes of major depression
Highly Cited
2006
Highly Cited
2006
Essential Role for Protein Kinase D Family Kinases in the Regulation of Class II Histone Deacetylases in B Lymphocytes
ABSTRACT We have taken a knockout approach to interrogate the function of protein kinase D (PKD) serine/threonine kinases in… 
Review
2006
Review
2006
Dichotomy of Ca2+ in the heart: contraction versus intracellular signaling.
Ca2+ plays a pivotal role in both excitation-contraction coupling (ECC) and activation of Ca2+-dependent signaling pathways. One… 
Highly Cited
2002
Highly Cited
2002
Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor*
BCL6 is a member of the POZ/zinc finger (POK) family involved in survival and/or differentiation of a number of cell types and in… 
Review
2001
Review
2001
Class II histone deacetylases: structure, function, and regulation.
Acetylation of histones, as well as non-histone proteins, plays important roles in regulating various cellular processes. Dynamic… 
Highly Cited
2000
Highly Cited
2000
Identification of a nuclear domain with deacetylase activity.
Here, we describe the identification and characterization of a nuclear body (matrix-associated deacetylase body) whose formation… 
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