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HCT 1026

Known as: HCT-1026, HCT1026, NCX-1026 
National Institutes of Health

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Broader (1)

nitroflurbiprofen

Papers overview

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2009
2009
The nitrosylated flurbiprofen derivative HCT1026 inhibits cytokine-induced signalling through a novel mechanism of action.
2009
2009
NO‐flurbiprofen reduces amyloid‐β, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade
The non‐steroidal anti‐inflammatory drug flurbiprofen is a selective amyloid lowering agent which has been studied clinically in… 
2007
2007
THE NITRIC OXIDE-RELEASING DERIVATIVE OF FLURBIPROFEN HCT1026 DECREASES VULNERABILITY OF NIGROSTRIATAL DOPAMINERGIC NEURONS TO MPTP VIA A SWITCH OF GLIA PROINFLAMMATORY PHENOTYPE: IMPLICATIONS FOR…
2005
2005
FLURBIPROFEN AND HCT1026 PROTECT MICE AGAINST ACUTE PANCREATITIS-ASSOCIATED LUNG INJURY
Impaired lung function in severe acute pancreatitis is the primary cause of morbidity and mortality in this condition… 
2004
2004
The flurbiprofen derivatives HCT1026 and HCT1027 inhibit bone resorption by a mechanism independent of COX inhibition and nitric oxide production.
2003
2003
Effect of HCT1026, a nitric oxide (NO) releasing derivative of flurbiprofen on gastrointestinal mucosa: a double blind placebo-controlled endoscopic study
2002
2002
Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study.
2002
2002
HCT 1026-A NOVEL TREATMENT FOR URGENCY ?
Aims of Study The human bladder is innervated by neuropeptide-containing sensory nerves which transmit sensations of bladder… 
2001
2001
Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026).
OBJECTIVE Inhibitors of prostaglandin production, such as nonsteroidal antiinflammatory drugs (NSAIDs), and pharmacologic nitric… 
1999
1999
HCT-1026 : TREATMENT OF SEPTIC SHOCK, TREATMENT OF URINARY INCONTINENCE, TREATMENT OF OSTEOPOROSIS, NITRIC OXIDE DONOR
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