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Glutethimide

Known as: 2,6-Piperidinedione, 3-ethyl-3-phenyl-, 2-Ethyl-2-phenylglutarimide, Glutethimide [Chemical/Ingredient] 
A hypnotic and sedative. Its use has been largely superseded by other drugs.
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (6)

4-hydroxyglutethimideDoridenNoxironcyclohexylaminoglutethimide
Drug AllergyGlutethimide:MCnc:Pt:Gast fld:QnGlutethimide:MCnc:Pt:Ser/Plas:QnGlutethimide:SCnc:Pt:Urine:Qn

Broader (5)

HypnoticsHypnotics and SedativesPiperidonesSedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC.
Highly Cited
2002
Highly Cited
2002
Immobilized halogenophenylcarbamate derivatives of cellulose as novel stationary phases for enantioselective drug analysis.
Highly Cited
1992
Highly Cited
1992
Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).
Highly Cited
1984
Highly Cited
1984
THALIDOMIDE IN SEVERE OROGENITAL ULCERATION
Highly Cited
1974
Highly Cited
1974
Successful medical adrenalectomy with amino-glutethimide. Role of altered drug metabolism.
We used amino-glutethimide and dexamethasone in patients with carcinoma of the breast to abolish adrenal steroidogenesis. Initial… 
Highly Cited
1968
Highly Cited
1968
Adsorption of drugs and poisons by activated charcoal.
Highly Cited
1967
Highly Cited
1967
Effects of amino-glutethimide on adrenal function in man.
ABSTRACT The effects of amino-glutethimide on adrenocortical function have been studied in 24 subjects, including 10 patients… 
Highly Cited
1967
Highly Cited
1967
Inhibition of adrenal corticosteroid synthesis by aminoglutethimide: studies of the mechanism of action.
ABSTRACT Amino-glutethimide inhibits corticosterone synthesis by the rat adrenal cortex both in vivo and in vitro. In intact rats… 
Highly Cited
1964
Highly Cited
1964
FURTHER STUDIES ON THE INHIBITION AND STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYMES OF RAT LIVER BY VARIOUS COMPOUNDS.
Highly Cited
1962
Highly Cited
1962
Induction of increased meprobamate metabolism in rats pretreated with some neurotropic drugs.
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