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Glutethimide
Known as:
2,6-Piperidinedione, 3-ethyl-3-phenyl-
, 2-Ethyl-2-phenylglutarimide
, Glutethimide [Chemical/Ingredient]
A hypnotic and sedative. Its use has been largely superseded by other drugs.
National Institutes of Health
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Related topics
Related topics
23 relations
Narrower (6)
4-hydroxyglutethimide
Doriden
Noxiron
cyclohexylaminoglutethimide
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Drug Allergy
Glutethimide:MCnc:Pt:Gast fld:Qn
Glutethimide:MCnc:Pt:Ser/Plas:Qn
Glutethimide:SCnc:Pt:Urine:Qn
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Broader (5)
Hypnotics
Hypnotics and Sedatives
Piperidones
Sedatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1987
Highly Cited
1987
Evidence for cytochrome P450-mediated oxidation of uroporphyrinogen by cell-free liver extracts from chick embryos treated with 3-methylcholanthrene.
P. Sinclair
,
Richard W. Lambrecht
,
J. Sinclair
Biochemical and Biophysical Research…
1987
Corpus ID: 35792438
Review
1984
Review
1984
Aminoglutethimide in the treatment of advanced breast cancer.
Robin C. Stuart-Harris
,
Ian E. Smith
Cancer Treatment Reviews
1984
Corpus ID: 45381362
Highly Cited
1973
Highly Cited
1973
Effects of various depressant drugs on deprivation-induced water consumption.
R. P. Maickel
,
G. J. Maloney
Neuropharmacology
1973
Corpus ID: 43013554
Highly Cited
1971
Highly Cited
1971
Accumulative prognostic index for patients with barbiturate, glutethimide and meprobamate intoxication.
Abdelmonem A. Afifi
,
Susan T. Sacks
,
Vinnie Y. Liu
,
Max Harry Weil
,
Herbert Shubin
New England Journal of Medicine
1971
Corpus ID: 28168532
Abstract To assess and update prognosis in a group of critically ill patients, repetitive measurements of physiologic status were…
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Highly Cited
1970
Highly Cited
1970
Hypnotics and altered sleep-dream patterns. I. All-night EEG studies of glutethimide, methyprylon, and pentobarbital.
A. Kales
,
T. Preston
,
T. Tan
,
C. Allen
Archives of General Psychiatry
1970
Corpus ID: 33414245
THE increasing variety of and demand for sedative and hypnotic drugs have created a dilemma for the physician. Until recently…
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1967
1967
Inhibition of Adrenal Steroidogenesis by Amino-Glutethimide and the Mechanism of Action
A. Camacho
,
R. Cash
,
A. J. Brough
,
R. Wilroy
1967
Corpus ID: 70969054
Four children with adrenal cortical hypofunction were receiving amino-glutethimide in combination with other anticonvulsants…
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1966
1966
Amino-glutethimide and metastatic adrenal cancer. Maintained reversal (six months) of Cushing's syndrome.
D. Schteingart
,
R. Cash
,
J. Conn
Journal of the American Medical Association (JAMA…
1966
Corpus ID: 28884471
Several compounds have been reported to effectively inhibit hormone production and neoplastic growth in patients with Cushing's…
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Highly Cited
1964
Highly Cited
1964
FURTHER STUDIES ON THE INHIBITION AND STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYMES OF RAT LIVER BY VARIOUS COMPOUNDS.
R. Kato
,
E. Chiesara
,
P. Vassanelli
Biochemical Pharmacology
1964
Corpus ID: 43540457
Highly Cited
1962
Highly Cited
1962
Induction of increased meprobamate metabolism in rats pretreated with some neurotropic drugs.
R. Kato
,
P. Vassanelli
Biochemical Pharmacology
1962
Corpus ID: 12922301
1960
1960
Asterixis in non-hepatic disorders.
H. Conn
American Journal of Medicine
1960
Corpus ID: 46180783
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