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Glutethimide

Known as: 2,6-Piperidinedione, 3-ethyl-3-phenyl-, 2-Ethyl-2-phenylglutarimide, Glutethimide [Chemical/Ingredient] 
A hypnotic and sedative. Its use has been largely superseded by other drugs.
National Institutes of Health

Papers overview

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1985
1985
Tumour ploidy, response and survival in patients receiving endocrine therapy for advanced breast cancer 
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Highly Cited
1974
Highly Cited
1974
We used amino-glutethimide and dexamethasone in patients with carcinoma of the breast to abolish adrenal steroidogenesis. Initial… Expand
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Highly Cited
1972
Highly Cited
1972
Because amino-glutethimide, an inhibitor of steroid synthesis, lowers the blood pressure of patients with essential hypertension… Expand
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Highly Cited
1969
Highly Cited
1969
Ten male volunteers received phenobarbital, glutethimide, chloral betaine, and a placebo at bedtime for 3 week periods. Plasma… Expand
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Highly Cited
1967
Highly Cited
1967
ABSTRACT The effects of amino-glutethimide on adrenocortical function have been studied in 24 subjects, including 10 patients… Expand
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Highly Cited
1967
Highly Cited
1967
ABSTRACT Amino-glutethimide inhibits corticosterone synthesis by the rat adrenal cortex both in vivo and in vitro. In intact rats… Expand
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1967
1967
Four children with adrenal cortical hypofunction were receiving amino-glutethimide in combination with other anticonvulsants… Expand
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1967
1967
ABSTRACT Thyroidal enlargement and hypothyroidism were observed in 3 children who had been treated for seizures with amino… Expand
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Highly Cited
1966
Highly Cited
1966
Data on the micellar solubilization of the poorly water-soluble drugs, griseofulvin, hexestrol, and glutethimide, in 0–0.6 M… Expand
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Highly Cited
1966
Highly Cited
1966
Studies of the influence of inorganic electrolyte on the solubilization of griseofulvin, glutethimide, and hexestrol in four… Expand
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