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Piperidones

Known as: Piperidones [Chemical/Ingredient], piperidone 
National Institutes of Health

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1,3-dimethyl-2-piperidinone1,5-dimethyl-2-piperidinone1-benzyl-4-piperidone1-methyl-3-carbomethoxy-piperidone-4
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Papers overview

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Highly Cited
2013
Highly Cited
2013
Synthesis and discovery of novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors.
Three-component reaction of a series of 1-acryloyl-3,5-bisbenzylidenepiperidin-4-ones with isatin and L-proline in 1:1:1 and 1:2… 
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Highly Cited
2013
Highly Cited
2013
A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.
The bis-benzylidine piperidone RA190 covalently binds to cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle… 
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2013
2013
Asymmetric conjugate addition of malonate esters to α,β-unsaturated N-sulfonyl imines: an expeditious route to chiral δ-aminoesters and piperidones.
The asymmetric conjugate addition of malonate esters to α,β-unsaturated N-sulfonyl imines is catalyzed by PyBOX/La(OTf)3… 
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Highly Cited
2011
Highly Cited
2011
Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.
A series of 3,5-bis(arylidene)-4-piperidone (DAP) compounds are considered as synthetic analogues of curcumin for anticancer… 
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Highly Cited
2010
Highly Cited
2010
Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells.
The development of smart anticancer drugs that can selectively kill cancer cells while sparing the surrounding healthy tissues… 
Highly Cited
2010
Highly Cited
2010
Anticancer Efficacy of a Difluorodiarylidenyl Piperidone (HO-3867) in Human Ovarian Cancer Cells and Tumor Xenografts
The purpose of this study was to evaluate the anticancer potency and mechanism of a novel difluorodiarylidenyl piperidone (H-4073… 
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Highly Cited
2003
Highly Cited
2003
Tetrahedron report number 638 Recent advances in the synthesis of piperidones and piperidines
1999
1999
Synthesis of Aryl-Substituted Piperidines by Superacid Activation of Piperidones.
Diarylpiperidines (8-12) may be prepared in good to excellent yields (80-99%) by the reaction of piperidones (3d-h) with benzene… 
Highly Cited
1975
Highly Cited
1975
Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.
Murine-virus-infected erythroleukemia cells cultured in a medium with dimethylsulfoxide or N,N-dimethylformamide are induced to… 
Highly Cited
1972
Highly Cited
1972
Composition and structure of the ornithine-containing lipid from Pseudomonas rubescens.
  • S. Wilkinson
  • Biochimica et biophysica acta
  • 1972
  • Corpus ID: 28953321
Abstract An ornithine-containing lipid was present in cells of Pseudomonas rubescens grown on nutrient agar, but not in those… 
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